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ADP ribosyl cyclase activity in rat parotid acinar cells.
European journal of morphology, 1999Cyclic ADP-ribose is an intracellular compound responsible for Ca2+ release in a wide variety of cell types. It may be implicated in releasing Ca2+ from ryanodine-sensitive pools in exocrine acinar cells. A bifunctional enzyme CD38 can synthesize cADP-ribose and we have characterized its properties by applying a technique in which nicotinamide guanine ...
Looms, D.K. +2 more
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Cyclic ADP-ribose, the ADP-ribosyl cyclase pathway and calcium signalling
Molecular and Cellular Endocrinology, 1994Cyclic adenosine diphosphate-ribose, an endogenous metabolite of nicotinamide adenine dinucleotide was first characterized as a potent Ca2+ mobilizing agent in sea urchin eggs. Mounting evidence points to it being an endogenous activator of Ca(2+)-induced Ca2+ release by non-skeletal muscle ryanodine receptors in several invertebrate and mammalian cell
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ADP-Ribosyl Cyclases - A Family of cADPR and NAADP Metabolizing Enzymes
2002ADP-ribosyl cyclase cyclizes NAD to produce cyclic ADP-ribose (cADPR) and releases nicotinamide in the process [1]. It is a ubiquitous enzyme widely present in animal cells [1, 2] and has even been identified in Euglena, a protozoan [4]. The first cyclase purified was from Aplysia ovotestis [1, 5].
Hon Cheung Lee +2 more
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Intermediates along the NAD+ cyclisation reaction pathway of ADP-ribosyl cyclase
2011Calcium is a ubiquitous, versatile intracellular signal regulating numerous cellular processes [1]. The versatility of Ca2+ signalling emerges from the use of an extensive repertoire of signalling components known as a Ca2+ signalling toolkit that can be assembled in combinations to create signals with different spatial and temporal profiles ...
Zhang, L +4 more
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Role of human CD38/ADP ribosyl cyclase for cell migration
Neuroscience Research, 2010Minako Hashii +3 more
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ADP-ribosyl cyclase coupled with muscarinic acetylcholine receptors via G proteins
Neuroscience Research, 1998H. Higashida +5 more
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[CD38 antigen (ADP-ribosyl cyclase) and secretory mechanism of insulin].
Nihon rinsho. Japanese journal of clinical medicine, 1998T, Taminato, T, Ito, H, Kato
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