Genome-Wide Linkage Analysis to Identify Chromosomal Regions Affecting Phenotypic Traits in the Chicken. III. Skeletal Integrity [PDF]
, 2007 Two unique chicken F2 populations generated from a broiler breeder male line and 2 genetically distinct inbred (\u3e99%) chicken lines (Leghorn and Fayoumi) were used for whole genome QTL analysis.
Ashwell, C. M. +6 more
core +3 more sources
Allergy, Volume 79, Issue 5, Page 1089-1122, May 2024.Abstract The accumulation of senescent cells drives inflammaging and increases morbidity of chronic inflammatory lung diseases. Immune responses are built upon dynamic changes in cell metabolism that supply energy and substrates for cell proliferation, differentiation, and activation.
F. Roth‐Walter +19 more
wiley +1 more source
Specificity of cholera toxin and mono(ADP-ribosyl)transferase activity in cultured myoblasts [PDF]
, 1990 The relationship between ADP-ribosylation and phosphorylation using a model substrate, the specificity requirements for cholera toxin-catalyzed ADP-ribosylation using peptide substrates, and the role of ADP-ribosylation reactions in skeletal muscle were ...
Kharadia, Shanta Virabhai
core +3 more sources
The hidden life of NAD+-consuming ectoenzymes in the endocrine system [PDF]
, 2010 Ectoenzymes are a family of cell surface molecules whose catalytic domain lies in the extracellular region. A subset of this family, nucleotide-metabolizing ectoenzymes, are key components in the regulation of the extracellular balance between ...
AUDRITO, VALENTINA +9 more
core +1 more source
Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina. [PDF]
, 2013 nherited retinal degenerations affecting both rod and cone photoreceptors constitute one of the causes 74 of incurable blindness in the developed world. Cyclic guanosine monophosphate (cGMP) is crucial in the 75 phototransduction and, mutations in genes ...
Aller Mañas, Elena +8 more
core +2 more sources
"Your funeral... my trial": a review of the mechanisms leading to cancer cells death when targeting nicotinamide adenine dinucleotide [PDF]
, 2014 Le nicotinamide adénine dinucléotide (NAD) est un métabolite jouant un rôle crucial dans la vie cellulaire. Dans la mitochondrie, il est surtout utilisé comme co-enzyme d'oxydo-réduction afin de produire de l'énergie sous forme d'ATP (respiration ...
MORISOD, L.
core
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. [PDF]
, 2002 The yeast silent information regulator (Sir)2 protein links cellular metabolism and transcriptional silencing through its nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase activity.
Frye, Roy A +4 more
core
The Ca2+-dependent Binding of Calmodulin to an N-terminal Motif of the Heterotrimeric G Protein beta Subunit [PDF]
, 1997 Ca2+ ion concentration changes are critical events in signal transduction. The Ca2+-dependent interactions of calmodulin (CaM) with its target proteins play an essential role in a variety of cellular functions.
Liu, Mingyao +4 more
core
ZFP36 proteins and mRNA targets in B cell malignancies [PDF]
, 2015 The ZFP36 proteins are a family of post-transcriptional regulator proteins that bind to adenine uridine rich elements (AREs) in 3’ untranslated (3’UTR) regions of mRNAs.
Alcaraz, A., Alcaraz, A.
core
The CD38/CD157 mammalian gene family: An evolutionary paradigm for other leukocyte surface enzymes [PDF]
, 2006 core +1 more source