Results 51 to 60 of about 2,983 (148)
Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes
, 2008 Proteins are macromolecules with characteristic structures and biological functions. It is extremely challenging to obtain protein microtube structures through self-assembly as proteins are very complex and flexible.
Hao, Q +11 more
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Molecular analysis of mammalian adenylyl cyclases and bacterial adenylyl cyclase toxins
, 2009 The cAMP signaling pathway is crucial for many physiological processes and many disease states like neurodegenerative diseases, mood disorders, pain, drug dependency or heart failure.
Göttle, Martin
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Identification and characterization of novel ADP-ribosyl cyclase family members
, 2011 University of Minnesota Ph.D. dissertation. August 2011. Major: Pharmacology. Advisor: Timothy F. Walseth Ph.D. 1 computer file (PDF); iv, 154 pages.CD38 and CD157 have been identified as mammalian forms of ADP-ribosyl cyclase (ADPRC).
Hirte, Renee Marie
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, 1996 cADPR is an endogenous calcium-mobilizing agent that in vertebrates is synthesized from nicotinamide-adenine dinucleotide (NAD) by bifunctional enzymes with ADP-ribosyl cyclase and cADPR hydrolase activity.
Ludmila Pawlikowska +4 more
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Efeito inibitório duradouro do óxido nítrico sobre a agregação plaquetária [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA agregação plaquetária ocorre fisiologicamente para ocluir lesões em vasos ou em condições anormais como na ...
Gonçalves, Muryel de Carvalho
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Structure, function and regulation of BP-3, a member of the CD38/ADP-ribosyl cyclase family
, 1996 The murine BP-3 gene encodes a variably glycosylated phosphatidylinositollinkcd cell surface glycoprotein that is expressed on early B and T lineage cells, myeloid cells, intestinal epithelial cells and a discrete population of reticular cells in ...
Cooper, MD +4 more
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An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle
, 2007 Previous investigations on pulmonary artery smooth muscle cells have shown that nicotinic acid adenine dinucleotide diphosphate (NAADP) evokes highly localised intracellular Ca²⁺ bursts by mobilising thapsigargin-insensitive Ca²⁺ stores.
Kinnear, Nicholas P.
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, 2005 International audienceADP-ribosyl cyclases are structurally conserved enzymes that are best known for catalyzing the production of the calcium-mobilizing metabolite, cyclic adenosine diphosphate ribose (cADPR), from nicotinamide adenine dinucleotide (NAD(
Kellenberger, Esther +11 more
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Does streptococcal ADP ribosyl cyclase/cADPR hydrolase evokeIgdassswitch?
, 2003 1.ある種の細胞において、精製レンサ球菌cADPR合成・分解酵素の添加によって細胞増殖抑制が観察された。この細胞増殖抑制効果はNADを添加した状態でも観察された。この細胞増殖抑制効果は,L929細胞Vero細胞、CHO細胞等の細胞株では観察されなかった。ハイブリドーマ細胞株を用いて、免疫グロブリンクラス・サブクラスの変化を観察したが、明確な免疫グロプリンクラススイッチは検出できなかった。 2.これまで本酵素をStreptococcus pyogenesの培養上清から精製してきたが、in ...
91562, 唐澤, 忠宏, 90251917
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Extracellular NAD is a regulator for FcγR-mediated phagocytosis in murine macrophages
, 2020 NAD is available in the extracellular environment and elicits immune modulation such as T cell apoptosis by being used as the substrate of cell surface ADP-ribosyl transferase.
심인경, 이승진
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