Results 111 to 120 of about 214,575 (242)

Interactional Endocytosis and Transmembrane Transport Promote Cellular Internalization of Nano‐Delivered RNA Drugs for Efficient Control of Crop Diseases

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Botrytis cinerea is a widespread plant pathogenic ascomycete that causes grey mould in over 1400 species and impacts global crop yields. Double‐stranded RNA (dsRNA)‐induced gene silencing is a promising technology for pest control, but efficient delivery remains a major challenge.
Mei Guan   +7 more
wiley   +1 more source

ADP-ribosylation factors: a family of ~20-kDa guanine nucleotide-binding proteins that activate cholera toxin

open access: yes, 1994
ADP-ribosylation factors (ARFs) comprise a family of ∼20 kDa guanine nucleotide-binding proteins that were discovered as one of several cofactors required in cholera toxin-catalyzed ADP-ribosylation of Gsα, the guanine nucleotide-binding protein ...
Moss, Joel   +6 more
core   +1 more source

Intracellular Mono-ADP-Ribosylation in Signaling and Disease

open access: yesCells, 2015
A key process in the regulation of protein activities and thus cellular signaling pathways is the modification of proteins by post-translational mechanisms.
Mareike Bütepage   +3 more
doaj   +1 more source

Serine is the major residue for ADP-ribosylation upon DNA damage

open access: yeseLife, 2018
Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that synthesise ADP-ribosylation (ADPr), a reversible modification of proteins that regulates many different cellular processes.
L. Palazzo   +5 more
semanticscholar   +1 more source

The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.

open access: yesPLoS Biology, 2008
ATP-dependent nucleosome-remodeling enzymes and covalent modifiers of chromatin set the functional state of chromatin. However, how these enzymatic activities are coordinated in the nucleus is largely unknown.
Anna Sala   +8 more
doaj   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

BIOCHEMICAL CHARACTERIZATION OF AUTO-ADP-RIBOSYLATED NARE

open access: yes, 2011
Mono ADP-ribosylation is a post-translational modification, conserved in viruses, prokaryotes and eukaryotes. Several ADP-ribose transfer enzymes as ART2, ART5, ExoS and CT are able to modify themselves, changing their chemical and biological functions ...
M. Picchianti   +2 more
core  

The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention‐deficit/hyperactivity disorder

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pregestational stress modifies germ‐cell epigenetic information, resulting in GABAergic dysfunction and E/I imbalance in the developing brain, thereby increasing susceptibility to ASD‐and ADHD‐related neurodevelopmental abnormalities in offspring.
Samaneh Ahmadian‐Moghadam   +2 more
wiley   +1 more source

Changes in NAD/ADP-ribose metabolism in rectal cancer

open access: yesBrazilian Journal of Medical and Biological Research, 2005
The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected during surgery from patients diagnosed as having rectal cancer on the basis of pathology results.
L. Yalcintepe   +5 more
doaj   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 4, Page 984-994, July 2026.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba   +4 more
wiley   +1 more source

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