Results 111 to 120 of about 214,575 (242)
ABSTRACT Botrytis cinerea is a widespread plant pathogenic ascomycete that causes grey mould in over 1400 species and impacts global crop yields. Double‐stranded RNA (dsRNA)‐induced gene silencing is a promising technology for pest control, but efficient delivery remains a major challenge.
Mei Guan +7 more
wiley +1 more source
ADP-ribosylation factors (ARFs) comprise a family of ∼20 kDa guanine nucleotide-binding proteins that were discovered as one of several cofactors required in cholera toxin-catalyzed ADP-ribosylation of Gsα, the guanine nucleotide-binding protein ...
Moss, Joel +6 more
core +1 more source
Intracellular Mono-ADP-Ribosylation in Signaling and Disease
A key process in the regulation of protein activities and thus cellular signaling pathways is the modification of proteins by post-translational mechanisms.
Mareike Bütepage +3 more
doaj +1 more source
Serine is the major residue for ADP-ribosylation upon DNA damage
Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that synthesise ADP-ribosylation (ADPr), a reversible modification of proteins that regulates many different cellular processes.
L. Palazzo +5 more
semanticscholar +1 more source
The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.
ATP-dependent nucleosome-remodeling enzymes and covalent modifiers of chromatin set the functional state of chromatin. However, how these enzymatic activities are coordinated in the nucleus is largely unknown.
Anna Sala +8 more
doaj +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
BIOCHEMICAL CHARACTERIZATION OF AUTO-ADP-RIBOSYLATED NARE
Mono ADP-ribosylation is a post-translational modification, conserved in viruses, prokaryotes and eukaryotes. Several ADP-ribose transfer enzymes as ART2, ART5, ExoS and CT are able to modify themselves, changing their chemical and biological functions ...
M. Picchianti +2 more
core
Abstract figure legend Pregestational stress modifies germ‐cell epigenetic information, resulting in GABAergic dysfunction and E/I imbalance in the developing brain, thereby increasing susceptibility to ASD‐and ADHD‐related neurodevelopmental abnormalities in offspring.
Samaneh Ahmadian‐Moghadam +2 more
wiley +1 more source
Changes in NAD/ADP-ribose metabolism in rectal cancer
The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected during surgery from patients diagnosed as having rectal cancer on the basis of pathology results.
L. Yalcintepe +5 more
doaj +1 more source
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba +4 more
wiley +1 more source

