Results 71 to 80 of about 105,381 (168)

Auxin‐related regulation of barley floral organ fate: genetic and phenotypic insights from tweaky spike mutants

New Phytologist, EarlyView.
Inflorescence/floret phenotypes of tweaky spike (tw) barley (Hordeum vulgare) mutants and their respective WT backgrounds. Summary Mutant‐based research is a cornerstone for elucidating gene function in barley (Hordeum vulgare) and other cereals. In this study, we exploited a unique collection of barley tweaky spike (tw) mutants to identify the locus ...
Vėjūnė Pukenytė, Bernadeta Kaminskaitė‐Mačė, Miglė Remeikytė, Jurga Jankauskienė, Julius Juodakis, Sigita Jurkonienė, Algė Leistrumaitė, Ljudmilla Timofejeva, Virginija Vaitkūnienė, Justas Stonkus, Raimondas Šiukšta   +10 more
wiley   +1 more source

Changes in NAD/ADP-ribose metabolism in rectal cancer

Brazilian Journal of Medical and Biological Research, 2005
The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected during surgery from patients diagnosed as having rectal cancer on the basis of pathology results.
L. Yalcintepe, L. Turker-Sener, A. Sener, G. Yetkin, D. Tiryaki, E. Bermek   +5 more
doaj   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

ENPP1 processes protein ADP-ribosylation in vitro. [PDF]

, 2016
ADP-ribosylation is a conserved post-translational protein modification that plays a role in all major cellular processes, particularly DNA repair, transcription, translation, stress response and cell death.
Nettleship, JE, Luca Palazzo, Osamu Nureki, Leung, AK, Kato, K, Ahel, I, Palazzo, Luca, Casey M. Daniels, Shao‐En Ong, Kazuki Kato, Robert Lyle McPherson, McPherson, RL, Joanne E. Nettleship, Ong, SE, Nahid Rahman, Rahman, Nahid, Daniels, CM, Nettleship, Joanne E, Nureki, O, Ivan Ahel, Rahman, N, Palazzo, L, Ahel, Ivan, Anthony K. L. Leung   +23 more
core   +3 more sources

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, Volume 101, Issue 5, Page 2103-2118, October 2026.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Reversing ADP-ribosylation

eLife, 2017
The modification of serines by molecules of ADP-ribose plays an important role in signaling that the DNA in a cell has been damaged and needs to be repaired.
Giuliana Katharina Moeller, Gyula Timinszky   +1 more
doaj   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo, Francesco Marocco, Clemens Zwergel, Marco Tripodi, Cecilia Battistelli   +4 more
wiley   +1 more source

ADP-ribosylation of BSA by Pertussigen Follows the same Mechanism as ADP-ribosylation of Transducine [PDF]

, 1986
Pertussigen is a toxin responsible for the ADP-ribosylation of the Adenylate cyclase system inhibitory component. It has been verified through polyacrylamide gel electrophoresis that the ADP-ribosylation occurs only if the reaction mixture is ...
Cabrera, John
core   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source