Results 151 to 160 of about 79,434 (274)

Stabilization versus flexibility: Detergent‐dependent trade‐offs in neurotensin receptor 1 GPCR ensembles

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Detergents provide essential membrane‐mimetic environments for studying G protein‐coupled receptors (GPCRs), but their molecular impact on receptor energetics remains incompletely understood. We combined ligand binding, thermostability measurements, and atomistic molecular dynamics to dissect detergent‐ versus ligand‐driven stabilization in a ...
James B. Bower, Wijnand J. C. van der Velden, Karen P. Gomez, Mingzhe Pan, Fabian Bumbak, Nagarajan Vaidehi, Joshua J. Ziarek   +6 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet, Belén Pepió‐Tárrega, Javier Saiz‐Poseu, Alba López‐Moral, Faiz Ullah, Victor J. Yuste, Daniel Ruiz‐Molina, Salvio Suárez‐García   +7 more
wiley   +2 more sources

Aβ and tau clearance through aerobic exercise: unveiling the β2-adrenergic receptor's role in regulating autophagy-lysosomal pathways. [PDF]

Autophagy Rep
Yang L, Yu H, Chai GS.
europepmc   +1 more source

Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.

Cell Regulation, 1990
K. Seuwen, I. Magnaldo, B. Kobilka, M. Caron, J. Regan, R. Lefkowitz, J. Pouysségur   +6 more
semanticscholar   +1 more source

Effects of alpha-adrenoceptor agonists and antagonists on adrenergic neurotransmitter overflow from dog isolated saphenous veins [proceedings].

, 1980
G.M. Drew, Andrew T. Sullivan
openalex   +1 more source

Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.

, 1987
L.M. Fredrik Leeb-Lundberg, Susanna Cotecchia, Antonio DeBlasi, Marc G. Caron, Robert J. Lefkowitz   +4 more
openalex   +1 more source

Acaricidal activity of small molecule antagonists of the tick kinin receptor against Rhipicephalus microplus acaricide‐susceptible and resistant strains

Pest Management Science, Volume 82, Issue 2, Page 1618-1628, February 2026.
Two small molecules, SACC‐0039590 and SACC‐0428788, killed cattle fever tick, R. microplus, susceptible Deutch strain and pyrethroid resistant Arauquita strain larvae. SACC‐0039590 at 1 mM decreased the reproductive parameters of Deutch females. Abstract BACKGROUND Resistance to acaricides underscores the need for tick control alternatives.
Waleed M. Arafa, Kimberly H. Lohmeyer, Patricia V. Pietrantonio   +2 more
wiley   +1 more source

Severe hyperglycaemia associated with prolonged isoflurane anaesthesia in an alpaca (Vicugna pacos)

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract Alpacas possess distinct glucose and insulin regulatory mechanisms compared with other species, often maintaining higher baseline blood glucose as a normal physiological adaptation. Inhalant anaesthetic agents can further disrupt glucose, insulin and potassium homeostasis, particularly during prolonged procedures.
Andrea Basler, Kathlyn Noelle Kuek, Friederike Pohlin, Ivana Calice   +3 more
wiley   +1 more source

Immuno-oncological effects of the α2-adrenoceptor agonist dexmedetomidine. [PDF]

Oncoimmunology
Bezu L, Kepp O, Kroemer G.
europepmc   +1 more source

Suspected pro‐arrhythmic effects of flecainide and the limitations of in‐hospital short‐duration electrocardiography in detecting ventricular arrhythmia burden in a dog with dilated cardiomyopathy

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 10‐year‐old, female, spayed Pitbull mix presented for evaluation of an arrhythmia. Echocardiography revealed enlargement of all cardiac chambers and decreased left ventricular systolic function. Electrocardiography demonstrated isolated, ventricular premature complexes.
Nathan Mitchell, Tamilselvam Gunasekaran, Robert Sanders, Joanne DeSana   +3 more
wiley   +1 more source