Results 91 to 100 of about 152,756 (198)
New neurons in aging brains: molecular control by small non-coding RNAs
Frontiers in Neuroscience, 2012 Adult neurogenesis is a process that continues in the adult and also aging brain. It generates functional neurons from neural stem cells present in specific brain regions.
Marijn eSchouten +3 more
doaj +1 more source
Serotonin and motherhood: From molecules to mood [PDF]
, 2019 Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming +2 more
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Weak universality in sensory tradeoffs [PDF]
, 2016 For many organisms, the number of sensory neurons is largely determined during development, before strong environmental cues are present. This is despite the fact that environments can fluctuate drastically both from generation to generation and within ...
DeDeo, Simon, Marzen, Sarah
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Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis [PDF]
, 2011 Injury and inflammation are potent regulators of adult neurogenesis. As the complement system forms a key immune pathway that may also exert critical functions in neural development and neurodegeneration, we asked if complement receptors regulate ...
Britschgi, Markus +9 more
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Astrocytes’ Contribution to Adult Neurogenesis in Physiology and Alzheimer’s Disease
Frontiers in Cellular Neuroscience, 2018 Adult neurogenesis is one of the most drastic forms of brain plasticity in adulthood and there is a growing body of evidence showing that, in the hippocampus, this process contributes to mechanisms of memory as well as depression.
Frédéric Cassé +2 more
doaj +1 more source
PLoS Genetics, 2013 The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and cognitive impairments. One hypothesis is that adult neurogenesis in the hippocampus enables spatial
James O Groves +8 more
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Depression and adult hippocampal neurogenesis
Folia Pharmacologica Japonica, 2010 現在，うつ病の治療薬はセロトニンやノルアドレナリンといったモノアミンを増加させる薬剤が中心として用いられているが，脳内の細胞外モノアミン濃度は抗うつ薬の投与数時間後には増加するのに対し，臨床における治療効果発現までには数週間の慢性投与が必要とされることもあり，抗うつ薬の治療発現メカニズムは未だ明らかとされていない．近年，成熟期の脳においても海馬歯状回といった特定領域において，神経幹・前駆細胞が存在し，神経細胞が新生されることが明らかにされている．この海馬における神経新生は，うつ病発症の危険因子とされるストレスによって抑制され，逆に抗うつ薬を慢性投与することによって促進される．さらに，海馬神経新生を阻害すると，行動薬理評価モデルにおける抗うつ薬の作用が消失するなどの報告から ...
Takahiro, Masuda +2 more
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Targeting Adult Neurogenesis for Poststroke Therapy
Stem Cells International, 2017 Adult neurogenesis mainly occurs at the subventricular zone (SVZ) on the walls of the lateral ventricle and the subgranular zone (SGZ) of the dentate gyrus (DG).
Jianfei Lu, Anatol Manaenko, Qin Hu
doaj +1 more source
Editorial: Functional Adult Neurogenesis [PDF]
Frontiers in Neuroscience, 2020 Gu, Y., Ge, S., Fitzsimons, C.P.
openaire +5 more sources
Functional implications of hypothalamic neurogenesis in the adult mammalian brain [PDF]
, 2012 Adult neurogenesis represents a striking example of structural plasticity in the mature brain. Research on adult mammalian neurogenesis today focuses almost exclusively on two areas: the subgranular zone (SGZ) in the dentate gyrus of the hippocampus, and
Blackshaw, Seth, Lee, Daniel A.
core