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Computational models of adult neurogenesis [PDF]
Physica A: Statistical Mechanics and its Applications, 2005 Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the context of and adult brain. Here we propose two models where new projection neurons are incorporated.
Cecchi, Guillermo A. +1 more
openaire +2 more sources
The maternal brain: an organ with peripartal plasticity. [PDF]
, 2014 The time of pregnancy, birth, and lactation, is characterized by numerous specific alterations in several systems of the maternal body. Peripartum-associated changes in physiology and behavior, as well as their underlying molecular mechanisms, have been ...
Aigner, Ludwig +7 more
core +1 more source
Reproduction: A New Venue for Studying Function of Adult Neurogenesis?
Cell Transplantation, 2011 Adult neurogenesis has been a focus within the past few years because it is a newly recognized form of neuroplasticity that may play significant roles in behaviors and recovery process after disease.
Benson Wui-Man Lau +2 more
doaj +1 more source
BDNF Haploinsufficiency Limits Voluntary Exercise-Induced Adult Hippocampal Neurogenesis
BiologyAdult hippocampal neurogenesis is involved in hippocampal plasticity and can be enhanced by voluntary physical activity, which also elevates “brain-derived neurotrophic factor” (BDNF) levels and improves memory performance. BDNF might either be essential
Monique Klausch +3 more
doaj +1 more source
Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease [PDF]
, 2006 The etiology of Alzheimer’s disease (AD) remains a great challenge for neurological research. Extensive investigations for almost one hundred years have led to profound insights of the pathological and molecular mechanisms that affect the AD brain, and
Ermini, Florian V.
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Factors that influence adult neurogenesis as potential therapy
Translational Neurodegeneration, 2018 Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside within distinct regions of the brain. This phenomenon was first described over 50 years ago and it is now firmly established that new neurons are continually ...
Belal Shohayeb +3 more
doaj +1 more source
Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin
Stem Cell Research & Therapy, 2022 Background Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the forebrain (BCAS2 cKO) of mice confers impaired learning and memory along with decreased β-catenin expression ...
Hsin-Hsiung Chen +11 more
doaj +1 more source
Adult Neurogenesis in Parkinson’s Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Its pathogenesis is based on diminution of neurons in the substantia nigra (SN) that under normal conditions acts as the source of dopamine in the nigrostriatal circuit ...
Mochizuki, Hideki
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LEARNING INDUCES THE EMERGENCE OF INDIVIDUALITY
IBRO Neuroscience Reports, 2023 Warsha Barde, Gerd Kempermann
doaj +1 more source
Developmental controls are re-expressed during induction of adult neurogenesis in the neocortex
Frontiers in Neuroscience, 2012 Whether induction of low-level neurogenesis in normally non-neurogenic regions of the adult brain mimics aspects of developmental neurogenesis is currently unknown.
U. Shivraj eSohur +2 more
doaj +1 more source