Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
, 2011 Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María +4 more
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Factors that influence adult neurogenesis as potential therapy
Translational Neurodegeneration, 2018 Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside within distinct regions of the brain. This phenomenon was first described over 50 years ago and it is now firmly established that new neurons are continually ...
Belal Shohayeb +3 more
doaj +1 more source
Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [PDF]
, 2011 The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works.
Azami, N.S. +3 more
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Frizzled-1 receptor regulates adult hippocampal neurogenesis [PDF]
, 2016 Indexación: Web of Science; Scopus.Background: In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus.
Andaur, G.A. +8 more
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The Impact of Ethologically Relevant Stressors on Adult Mammalian Neurogenesis
Brain Sciences, 2019 Adult neurogenesis—the formation and functional integration of adult-generated neurons—remains a hot neuroscience topic. Decades of research have identified numerous endogenous (such as neurotransmitters and hormones) and exogenous (such as ...
Claudia Jorgensen +2 more
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Breast carcinoma-amplified sequence 2 regulates adult neurogenesis via β-catenin
Stem Cell Research & Therapy, 2022 Background Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the forebrain (BCAS2 cKO) of mice confers impaired learning and memory along with decreased β-catenin expression ...
Hsin-Hsiung Chen +11 more
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Adult neurogenesis 20 years later: physiological function vs. brain repair [PDF]
, 2015 The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity.
Luca Bonfanti, Paolo Peretto
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Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans. [PDF]
, 2014 To better understand the role of radial glial (RG) cells in the evolution of the mammalian cerebral cortex, we investigated the role of RG cells in the dorsal cortex and dorsal ventricular ridge of the turtle, Trachemys scripta elegans.
Clinton, Brian K +4 more
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Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
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Waste Management and Adult Neurogenesis [PDF]
Cell Stem Cell, 2010 Dying cells are common in adult neurogenic niches, but how these cells are cleared remains uncertain. In this issue of Cell Stem Cell, Sierra et al. (2010) show that unactivated microglia assume the role of waste managers to eliminate cellular debris from apoptosing newborn cells in the hippocampus.
Mattocks, Michael, Tropepe, Vincent
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