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Advanced Glycation End Products and Psoriasis

Vaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni   +2 more
doaj   +4 more sources

Sex-specific differences of advanced glycation end products in diabetes [PDF]

Nutrition & Diabetes
Advanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig, Julia Decker, Leticia Prates Roma, Stefan Schunk, Emmanuel Ampofo, Sandra Rother   +5 more
doaj   +2 more sources

Lack of receptor for advanced glycation end products attenuates obesity-induced adipose tissue senescence in mice. [PDF]

Adipocyte
Du Z, Wu J, Zhang T, Ma X, Li Z, Xu J, You J, Chen N, Wu J.   +8 more
europepmc   +2 more sources

Clearance Kinetics and Matrix Binding Partners of the Receptor for Advanced Glycation End Products [PDF]

, 2014
Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE).
Pavle S. Milutinovic, Judson M. Englert, Lauren T. Crum, N. Scott Mason, Lasse Ramsgaard, Jan J. Enghild, Louis J. Sparvero, Michael T. Lotze, Tim D. Oury   +8 more
openalex   +5 more sources

Effects of advanced glycation end products on stem cell [PDF]

Frontiers in Cell and Developmental Biology
In recent years, stem cell therapy has become a pivotal component of regenerative medicine. Stem cells, characterized by their self-renewal capacity and multidirectional differentiation potential, can be isolated from a variety of biological tissues ...
Zetai Zheng, Hui Zhou, Wenwen Zhang, Tingyu Wang, Sathiskumar Swamiappan, Xinsheng Peng, Yanfang Zhou   +6 more
doaj   +2 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

Біологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak, H. Ya. Hachkova, N. O. Sybirna   +2 more
doaj   +1 more source

Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

Frontiers in Molecular Biosciences, 2022
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels.
Misganaw Asmamaw Mengstie, Endeshaw Chekol Abebe, Awgichew Behaile Teklemariam, Anemut Tilahun Mulu, Melaku Mekonnen Agidew, Muluken Teshome Azezew, Edgeit Abebe Zewde, Assefa Agegnehu Teshome   +7 more
doaj   +1 more source

Advanced glycation end products and cognitive impairment in schizophrenia.

PLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori, Mitsuhiro Miyashita, Yasuhiro Miyano, Kazuhiro Suzuki, Kazuya Toriumi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Akane Yoshikawa, Yasue Horiuchi, Syudo Yamasaki, Atsushi Nishida, Satoshi Usami, Shunya Takizawa, Masanari Itokawa, Heii Arai, Makoto Arai   +17 more
doaj   +1 more source

Advanced glycation end products modulate electrophysiological remodeling of right ventricular outflow tract cardiomyocytes: A novel target for diabetes‐related ventricular arrhythmogenesis

Physiological Reports, 2022
Diabetes mellitus is associated with cardiovascular disease and cardiac arrhythmia. Accumulation of advanced glycation end products closely correlates with cardiovascular complications through mitochondrial dysfunction or oxidative stress and evoke ...
Yao‐Chang Chen, Yen‐Yu Lu, Wen‐Shiann Wu, Yung‐Kuo Lin, Yi‐Ann Chen, Shih‐Ann Chen, Yi‐Jen Chen   +6 more
doaj   +1 more source

The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]

Diabetes & Metabolism Journal, 2018
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
doaj   +1 more source