Results 21 to 30 of about 94,238 (337)

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

PLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt   +9 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

Translational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner   +20 more
doaj   +1 more source

NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification [PDF]

, 2005
The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to ...
Howard, Mark J., Smales, Christopher Mark   +1 more
core   +1 more source

Advanced Glycation End Products in Health and Disease

Microorganisms, 2022
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah   +2 more
doaj   +1 more source

Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]

, 2018
The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A, Currier, Judith S, Danoff, Ann, Kelesidis, Theodoros, Kendall, Michelle A, Schmidt, Ann Marie   +5 more
core   +1 more source

Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue [PDF]

, 2017
Concurrent with a progressive loss of regenerative capacity, connective tissue aging is characterized by a progressive accumulation of Advanced Glycation End-products (AGEs).
Andreassen, Ansari, Avery, Bailey, Bedi, Cheng, Del Turco, Dressler, Dyer, Fessel, Fessel, Fessel, Fratzl, Gautieri, Gautieri, Gautieri, Goh, Goh, Grandhee, Gupta, Hansen, Kraft, Lavagnino, Li, Li, Meier, Monnier, Nagaraj, Nair, Reddy, Reigle, Rigoldi, Sasaki, Schnider, Sell, Sell, Sensi, Slatter, Snedeker, Sroga, Su, Su, Svensson, Svensson, Szczesny, Szczesny, Tanaka, Tang, Tang, Thorpe, Toyama, Vashishth, Verzijl, Verzijl, Vesentini, Vincent, Willett, Wu, Yamagishi, Zimmermann   +59 more
core   +2 more sources

Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]

, 2015
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh, Chello, Massimo, DI DOMENICO, Fabio, Nappi, Francesco, Nenna, Antonio, Spadaccio, Cristiano, Sutherland, Fraser W   +6 more
core   +2 more sources

Advanced glycation end products as a biomarker for incisional hernia [PDF]

, 2017
Background: Incisional hernia is one of the most frequent complications after abdominal surgery, with incidences up to 30%. A reliable biomarker for the prediction of this complication is lacking. Advanced glycosylation end products (AGEs), also known as
Cabezas, M.C., Eker, H.H. (Hasan), Ham, A.C. (Arie) van der, Harlaar, J.J. (Joris Jan), Jeekel, J. (Hans), Lange, J.F. (Johan), Vakalopoulos, K.A. (Konstantinos), Vrijland, W.W. (Wietske)   +7 more
core   +4 more sources

Skin advanced glycation end-products evaluation in infants according to the type of feeding and mother’s smoking habits

SAGE Open Medicine, 2016
Objectives: This study was conducted to assess whether formula-fed infants had increased skin advanced glycation end-products compared with breastfed ones.
Giovanni Federico, Martina Gori, Emioli Randazzo, Francesco Vierucci   +3 more
doaj   +1 more source

Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce

Біологічні студії, 2022
As leukocytes represent cellular and humoral immunity at the same time, they are a vital part of every immune process. This also stands for autoimmune processes and disorders, such as diabetes, specifically type 1 diabetes mellitus.
О. М. Kuchurka, М. O. Chaban, O. V. Dzydzan, I. V. Brodyak, N. O. Sybirna   +4 more
doaj   +1 more source