Results 161 to 170 of about 42,960 (301)

In vitro and in silico studies and a systematic literature review of antiglycation properties of amlodipine

Scientific Reports
Protein glycation is crucial in the pathogenesis of diabetes and its cardiovascular complications. Little is known about the antiglycation properties of amlodipine, a long-acting calcium channel blocker used to treat high blood pressure.
Karolina Dańkowska, Miłosz Nesterowicz, Kamil Klaudiusz Lauko, Daria Trocka, Małgorzata Żendzian-Piotrowska, Jerzy Robert Ładny, Anna Zalewska, Marta Żebrowska-Gamdzyk, Mateusz Maciejczyk   +8 more
doaj   +1 more source

In Vitro Methodologies to Study the Role of Advanced Glycation End Products (AGEs) in Neurodegeneration. [PDF]

Nutrients, 2022
Chrysanthou M, Miro Estruch I, Rietjens IMCM, Wichers HJ, Hoppenbrouwers T.   +4 more
europepmc   +1 more source

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

Journal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei, Michele Baldari, Lorenzo Brognara, Enrico Saudelli, Simona Moscatiello, Sara Flamigni, Francesco Traina, Alexandro Paccapelo, Uberto Pagotto, Guido Di Dalmazi   +9 more
wiley   +1 more source

Body mass index and peripheral neuropathy across the glucose tolerance spectrum in Japanese adults

Journal of Diabetes Investigation, EarlyView.
Graphical illustration of participant classification by metabolic status (normoglycemic, IGT, type 2 diabetes mellitus) and BMI with key neurological and metabolic assessments. In Japanese adults, obesity at the Japanese BMI threshold (≥25 kg/m2) is associated with adverse metabolic profiles across all glycemic states but exacerbates peripheral ...
Fukashi Ishibashi, Aiko Kosaka, Harumi Uetake, Darren C. Greenwood, Laura Güdemann, Hassan Fadavi, Mitra Tavakoli   +6 more
wiley   +1 more source

A Systematic Review on the Role of Advanced Glycation End-products (AGEs) in the Development of PCOS

JLUMHS
This review was done to investigate the research done globally and in Pakistan about the role of AGEs in developing PCOS. Literature was searched at any time by using Google Scholar and PubMed.
Yasmin Akhtar, Salma Malik, Muna Bhutta, Sara Muhammad Atta Almanan, Tahira Bashir Solehria, Muhammad Kashif Malik   +5 more
doaj   +1 more source

INCREASED DIETARY INTAKE AND SERUM LEVELS OF ADVANCED GLYCATION END PRODUCTS (AGES) ARE ASSOCIATED WITH DIABETIC MACULAR EDEMA. [PDF]

Acta Endocrinol (Buchar), 2022
Arslan S, Kiraği D, Kadayifçilar S, Samur G.   +3 more
europepmc   +1 more source

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma, Takahiro Tsutsumi, Asako Miyazaki, Kyoichiro Tsuchiya   +3 more
wiley   +1 more source

Chemical Composition of Hazelnut Skin Food Waste and Protective Role against Advanced Glycation End-Products (AGEs) Damage in THP-1-Derived Macrophages. [PDF]

Molecules, 2023
Spagnuolo L, Della Posta S, Fanali C, Dugo L, De Gara L.   +4 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Association of Autofluorescent Advanced Glycation End Products (AGEs) with Frailty Components in Chronic Kidney Disease (CKD): Data from a Single-Center Cohort Study. [PDF]

Cells, 2023
Molinari P, Caldiroli L, Dozio E, Rigolini R, Giubbilini P, Carminati FMI, Castellano G, Corsi Romanelli MM, Vettoretti S.   +8 more
europepmc   +1 more source