Results 181 to 190 of about 24,686 (257)

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

open access: yesBioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen   +2 more
wiley   +1 more source

Burden of Diabetes as a Contributing Cause in Dementia Mortality Among Older Adults in the United States, 1999–2020

open access: yesBrain and Behavior, Volume 16, Issue 7, July 2026.
Among 3.8 million dementia‐related deaths in U.S. adults aged ≥65 years during 19992020, diabetes was documented in 6.2%. Mortality increased sharply until 2009 and then stabilized, with substantial age, racial/ethnic, and geographic disparities, highlighting the need for targeted prevention and continued surveillance. ABSTRACT Background Diabetes is a
Aasim Ali   +14 more
wiley   +1 more source

Roles of Microglia in Cerebral Small Vessel Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Chronic cerebral hypoperfusion triggers microglial activation in cerebral small vessel disease (CSVD). Activated microglia drive neuroinflammation, oxidative stress, and blood–brain barrier disruption, leading to white matter hyperintensities, enlarged perivascular spaces, and other neuroimaging features.
Chenyang Jin   +7 more
wiley   +1 more source

Advanced Glycation End Products of Maillard Reaction and Aging.

open access: yesJournal of the Japan Society of the Reticuloendothelial System, 1996
Takeya, Motohiro, Takahashi, Kiyoshi
openaire   +2 more sources

Serum Advanced Glycation End Products as Drivers of Poor Tendon Outcomes in Diabetes? An Emerging Hypothesis and Narrative Review

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Tendon injuries in diabetes heal poorly, with unclear drivers of extracellular matrix disruption and altered mechanics. This narrative review synthesizes in vitro, animal, and human studies, highlighting serum advanced glycation end products as potential systemic contributors.
Eric J. Gutierrez   +3 more
wiley   +1 more source

Oxidative Stress‐Induced Expression Levels of PXDN and NF‐κB in Type 2 Diabetic Patients With Nephropathy

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
PXDN expression is markedly upregulated in diabetic nephropathy and, versus NF‐κB and oxidative stress markers, shows superior diagnostic performance (AUC 0.79; 90% specificity), supporting PXDN as a sensitive, specific non‐invasive biomarker for early DN.
Zakira Hanin   +6 more
wiley   +1 more source

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