Results 191 to 200 of about 24,686 (257)

Associations between Serum Zinc Levels and the Presence of Distal Symmetric Polyneuropathy in Patients with Type 2 Diabetes Mellitus

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Lower serum zinc levels were independently associated with distal symmetric polyneuropathy in patients with type 2 diabetes mellitus. Each 1 μg/dL increase in serum zinc level was associated with a 5.4% reduction in the odds of diabetic neuropathy, suggesting a potential role of zinc deficiency in DSPN pathogenesis.
Hosseinali Mohammadi, Firozeh Sajedi, Younes Mohammadi   +2 more
wiley   +1 more source

FZD7 Inhibitor SRI Attenuates High Glucose‐Induced Retinal Pigment Epithelial Cell Injury Accompanied by Ferroptosis‐Associated Changes via Suppression of the Wnt/β‐Catenin Pathway

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
SRI inhibits FZD7/Wnt/β‐catenin to upregulate DHODH/FSP1, alleviating ferroptosis, oxidative stress and mitochondrial damage against high glucose‐induced ARPE‐19 injury. ABSTRACT Purpose This study investigated the protective effects of the Frizzled‐7 (FZD7) inhibitor SRI against high glucose–induced injury in human retinal pigment epithelial (ARPE‐19)
Jiaojiao Jiang, Liu Zheng, Liwu Tan, Zhixiang Ding   +3 more
wiley   +1 more source

Thermal, Structural, and Molecular Characterization of a Model Cereal–Milk Infant Formula: Impact of Ultrasound Pre‐Treatment Prior to Spray Drying

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study evaluated the efficacy of an ultrasound pre‐treatment applied to a complex cereal–milk infant formula prior to conventional spray drying to mitigate inherent stickiness and yield challenges. Acoustic cavitation (30–90 s) significantly reduced suspension viscosity and improved atomization efficiency, elevating powder recovery yield from 12 ...
Yamen Barakat, Ilyas Atalar, Nevzat Konar   +2 more
wiley   +1 more source

Associations of Dietary Patterns and Micronutrients With Major Adverse Cardiovascular Events and Mortality Among Populations With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0–3: Results From Two Prospective Cohorts

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Graphical abstract illustrating the study design and core findings of two prospective cohorts (UK Biobank, n = 82,222; NHANES, n = 16,842) enrolling participants with CKM syndrome stages 0–3. We examined associations of plant‐based diets (HPDI, AMED), pro‐inflammatory diet (DII), and multiple micronutrients (vitamins, minerals) with MACE and all‐cause ...
Yingqi Hou, Kaixin Yuan, Yadan Xu, Wen Gu, Tian Wang, Tangyi Su, Yangchen Lhamu, Yanqiu Huang, Shuli Li, Jinjin Liu, Honglin Liu, Wentao Shi   +11 more
wiley   +1 more source

Exploring the Therapeutic Potential of Oenothera laciniata: Antioxidant, Anti‐Hyperglycemic and Histopathological Activities Using In Vitro and In Vivo Approaches

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Graphical abstract illustrating the therapeutic potential of Oenothera laciniata: antioxidant, anti‐hyperglycemic and histopathological activities using in vitro and in vivo approaches. ABSTRACT This study investigate the crude ethanolic extract of Oenothera laciniata (EOL) and its solvent fractions n‐hexane (NHOL), dichloromethane (DCMOL), ethyl ...
Dur‐E‐Najaf Khan, Syed Muhammad Mukarram Shah, Muska Mahabat Khan, Rehman Zafar, Muhammad Saeed Jan, Muhammad Ibrar, Abdur Rauf, Yahya S. Al‐Awthan, Omar S. Bahattab, Rakibur Rahman   +9 more
wiley   +1 more source

Pharmacological and Pharmacokinetic Profiling of Asphodelus microcarpus Phytochemicals: UHPLC–MS/MS Characterization, Molecular Docking, and ADMET Analysis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Bioactive phytochemicals from Asphodelus microcarpus exhibited significant antioxidant and antidiabetic potential. In silico analyses confirmed favorable target interactions and pharmacokinetic properties, highlighting its therapeutic promise. ABSTRACT This study investigates the phytochemical composition and biological activities of Asphodelus ...
Mohammed Roubi, Youness Mahdi, Ayoub Farihi, Chahrazad Belkhiri, Mohammed Dalli, Salah‐Eddine Azizi, Nour Elhouda Daoudi, Raffaele Conte, Mohammed Hawwal, Mohammed Alzahrani, Omer M. Almarfadi, Nadia Gseyra, Ramzi A. Mothana   +12 more
wiley   +1 more source

Evaluating the Hepatoprotective Effect of Phyllanthus emblica and Panax ginseng Powders on Acetaminophen‐Induced Liver Fibrosis in a Rat Model

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic illustration of the experimental design and the hepatoprotective effect of Phyllanthus emblica and Panax ginseng against acetaminophen (APAP)‐induced fibrosis in Wistar rats. APAP administration leads to NAPQI formation and accumulation, which causes GSH depletion and HSC activation. This ultimately becomes the primary cause of liver fibrosis.
Fiza Javed, Nourah Harbi Almutairi, Wardha Tariq, Mah Noor, Shiza Javed, Usman Haider, Ghalia Shamlan, Gholamreza Abdi, Rana Muhammad Aadil   +8 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Biomimetic Collagen Scaffolds Natural Cross‐Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair

Journal of Biomedical Materials Research Part A, Volume 114, Issue 7, July 2026.
ABSTRACT Collagen‐based scaffolds are widely used in tissue engineering for skin repair due to their biocompatibility and structural resemblance to extracellular matrix. However, rapid degradation and insufficient mechanical stability limit their effectiveness. This study investigates natural cross‐linking strategies utilizing Transglutaminase (TG) and
Mina Vaez, Matthew Yen, Aiman Ali, Sophia Huang, Liyang Zhong, Christina M. Schuh, Laurent Bozec   +6 more
wiley   +1 more source