Results 191 to 200 of about 42,960 (301)

Fingerprinting the Intestinal Transport of Low-Molecular-Mass Advanced Glycation End-Products (AGEs) Using a Caco-2 Transwell Model. [PDF]

J Agric Food Chem
Li X, Wesseling S, Sang Y, Rietjens IMCM.   +3 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Advanced glycation end-products (AGEs) are lower in prostate tumor tissue and inversely related to proportion of West African ancestry. [PDF]

Prostate, 2022
Zenner ML, Helou YB, Deaton RJ, Sverdlov M, Wang H, Kajdacsy-Balla A, Macias V, Voisine C, Murray M, Abdulkadir SA, Murphy AB, Nonn L.   +11 more
europepmc   +1 more source

Study on the inhibitory effects and mechanisms of four polyphenolic compounds from perilla extract on advanced glycation end products (AGEs). [PDF]

Food Chem X
Han X, Sun X, Shi Z, Fan X, Hu Y, Chen C, Xia Q, Sun Y, Pan D.   +8 more
europepmc   +1 more source

Natural Antioxidants and Hydrocolloids as a Mitigation Strategy to Inhibit Advanced Glycation End Products (AGEs) and 5-Hydroxymethylfurfural (HMF) in Butter Cookies. [PDF]

Foods, 2022
Hu H, Wang Y, Huang Y, Yu Y, Shen M, Li C, Nie S, Xie M.   +7 more
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Relationships between advanced glycation end products (AGEs), vasoactive substances, and vascular function. [PDF]

J Smooth Muscle Res, 2021
Matsumoto T, Taguchi K, Kobayashi T.
europepmc   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Clinical factors associated with advanced glycation end-products (AGEs) levels evaluated by skin autofluorescence of schoolchildren in Japan. [PDF]

Clin Pediatr Endocrinol
Nagahara K, Motegi S, Ochi A, Toyoda J, Nakano Y, Imai T, Adachi M, Yamagishi SI, Mizuno K.   +8 more
europepmc   +1 more source