Results 231 to 240 of about 42,960 (301)
Advanced Glycation End Products of Maillard Reaction and Aging.
Motohiro Takeya, Kiyoshi Takahashi
openaire +2 more sources
This study shows that urinary nephrin and related podocyte injury markers are elevated among people living with diabetes in Ghana, particularly those with macroalbuminuria. Nephrin demonstrated discriminatory ability, supporting its role as an exploratory biomarker for diabetic nephropathy rather than a standalone diagnostic tool.
Helen Owusu‐Asante +3 more
wiley +1 more source
Protocatechuic acid attenuates D‐gal‐induced renal aging through regulation of CSAD‐mediated taurine metabolism, thereby alleviating oxidative stress and inflammation. ABSTRACT Protocatechuic acid (PCA), a natural phenolic compound with antioxidant and anti‐inflammatory properties, has been proposed as a potential therapeutic agent against aging ...
Songhao Tian +6 more
wiley +1 more source
This study employs an interpretable machine learning framework to predict diabetes‐cancer comorbidity, with the Random Forest and LightGBM models demonstrating exceptional performance. SHAP value analysis reveals that while advanced age and cardiometabolic dysfunctions serve as primary risk drivers, dietary antioxidants (particularly daidzein and ...
Ming Xu +8 more
wiley +1 more source
Neuroprotective Effects of Carnosine Against Corticosterone‐Induced Depression and Memory Impairment
This main findings of the study and illustrates the key workflow. ABSTRACT Corticosterone (Crt) is reported to induce oxidative stress in experimental animals. Carnosine (Crn), a well‐known dipeptide antioxidant synthesized endogenously from β‐alanine and L‐histidine, neutralizes oxidative stress. The current study examines the influences of Crn on Crt‐
Muneezah Elahi +6 more
wiley +1 more source
This study based on NHANES 2011–2018 (16,154 adults) found that higher LC9 score is an independent protective factor for rheumatoid arthritis (RA), with each 1‐unit increase associated with a 27% lower risk (OR = 0.73). An XGBoost machine learning model integrating LC9 and clinical covariates achieved excellent predictive performance (test AUC = 0.987).
Jiasi Zheng +6 more
wiley +1 more source
ABSTRACT Introduction Obsessive‐compulsive disorder (OCD) is a complex neuropsychiatric disorder indicated by intrusive thoughts and recurrent actions. Glyoxalase‐1 (GLO‐1) is a metabolic enzyme linked to numerous psychiatric disorders, and its role in OCD remains elusive.
Salsabil Islam +3 more
wiley +1 more source
Quercetin and melatonin, alone or combined, effectively protect the liver in diabetic rats. The antioxidants reduce hyperglycemia, oxidative stress, and inflammation, preventing hepatic damage. ABSTRACT Liver complications in diabetes are very common, contributing to a high mortality rate, making it essential to develop strategies to minimize this ...
Érique Ricardo Alves +10 more
wiley +1 more source

