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Aerobic Glycolysis: A DeOxymoron of (Neuro)Biology [PDF]

Metabolites, 2022
The term ‘aerobic glycolysis’ has been in use ever since Warburg conducted his research on cancer cells’ proliferation and discovered that cells use glycolysis to produce adenosine triphosphate (ATP) rather than the more efficient oxidative ...
Avital Schurr, Salvatore Passarella
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HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification

Cell Death Discovery, 2023
Aerobic glycolysis has been shown to play a key role in tumor cell proliferation and metastasis. However, how it is directly regulated is largely unknown.
Jiayu Wang, Mengxin Zhu, Jinghan Zhu, Juntao Li, Xingchao Zhu, Kun Wang, Kanger Shen, Kexi Yang, Xiangyu Ni, Xin Liu, Guangbo Zhang, Qinhua Xi, Tongguo Shi, Weichang Chen   +13 more
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SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

Frontiers in Cell and Developmental Biology, 2022
Increased dependence on aerobic glycolysis is characteristic of most cancer cells, whereas the mechanism underlying the promotion of aerobic glycolysis in metastatic breast cancer cells under ambient oxygen has not been well understood.
Chenguang Yao, Jun Weng, Lingyun Feng, Wanjun Zhang, Yan Xu, Peijing Zhang, Yoshimasa Tanaka, Li Su   +7 more
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Aerobic glycolysis: beyond proliferation. [PDF]

Frontiers in Immunology, 2015
Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review we will discuss some recent findings to illustrate
William eJones, Katiuscia eBianchi
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A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5

Journal of Experimental & Clinical Cancer Research, 2022
Background RNA-binding proteins (RBPs) and circular RNAs (circRNAs) play important roles in glioblastoma multiforme (GBM). Aerobic glycolysis is a metabolic characteristic of GBM.
Jian Song, Jian Zheng, Xiaobai Liu, Weiwei Dong, Chunqing Yang, Di Wang, Xuelei Ruan, Yubo Zhao, Libo Liu, Ping Wang, Mengyang Zhang, Yunhui Liu   +11 more
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Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis

Frontiers in Oncology, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Yanbo Zhu, Fang Li, Yilong Wan, Yilong Wan, Hansi Liang, Si Li, Bo Peng, Bo Peng, Liqun Shao, Liqun Shao, Yunyun Xu, Dong Jiang, Dong Jiang   +12 more
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The role and mechanism of aerobic glycolysis in nasopharyngeal carcinoma [PDF]

PeerJ
This review delves into the pivotal role and intricate mechanisms of aerobic glycolysis in nasopharyngeal carcinoma (NPC). NPC, a malignancy originating from the nasopharyngeal epithelium, displays distinct geographical and clinical features. The article
Zhiyong Pan, Yuyi Liu, Hui Li, Huisi Qiu, Pingmei Zhang, Zhiying Li, Xinyu Wang, Yuxiao Tian, Zhengfu Feng, Song Zhu, Xin Wang   +10 more
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Proton export upregulates aerobic glycolysis

BMC Biology, 2022
Aggressive cancers commonly ferment glucose to lactic acid at high rates, even in the presence of oxygen. This is known as aerobic glycolysis, or the “Warburg Effect.” It is widely assumed that this is a consequence of the upregulation of glycolytic ...
Shonagh Russell, Liping Xu, Y. Kam, D. Abrahams, Bryce Ordway, Alexis S. Lopez, M. Bui, Joseph Johnson, T. Epstein, Epifanio Ruiz, M. Lloyd, P. Swietach, Daniel Verduzco, Jonathan W. Wojtkowiak, R. Gillies   +14 more
semanticscholar   +4 more sources

Brain aerobic glycolysis and resilience in Alzheimer disease

Proceedings of the National Academy of Sciences, 2022
The distribution of brain aerobic glycolysis (AG) in normal young adults correlates spatially with amyloid-beta (Aβ) deposition in individuals with dementia of the Alzheimer type (DAT) and asymptomatic individuals with brain amyloid deposition.
M. Goyal, Tyler M. Blazey, Nicholas V. Metcalf, M. McAvoy, Jeremy F. Strain, Maryam Rahmani, T. Durbin, C. Xiong, T. Benzinger, J. Morris, M. Raichle, A. Vlassenko   +11 more
semanticscholar   +4 more sources

Regulation of drug resistance in bladder urothelial carcinoma by tumor aerobic glycolysis [PDF]

Journal of Translational Medicine
Background Bladder urothelial carcinoma (BUC) is one of the most common malignant tumors of the urinary system, and its drug resistance often leads to treatment failure and high mortality.
Can Weng, Hao Deng, Ziyang Yang, Xi Zeng, Haoxuan Xu, Jiuru Li, Chunping Yu   +6 more
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