Results 21 to 30 of about 339,203 (181)

Role of glycolysis in retinal vascular endothelium, glia, pigment epithelium, and photoreceptor cells and as therapeutic targets for related retinal diseases [PDF]

International Journal of Ophthalmology, 2021
Glycolysis produces large amounts of adenosine triphosphate (ATP) in a short time. The retinal vascular endothelium feeds itself primarily through aerobic glycolysis with less ATP.
Ting-Ting Yang, Hui Li, Li-Jie Dong
doaj   +1 more source

Comprehensive analysis of aerobic glycolysis-related genes for prognosis, immune features and drug treatment strategy in prostate cancer

Frontiers in Oncology, 2022
BackgroundThe dysregulated expression of aerobic glycolysis-related genes is closely related to prostate cancer progression and metastasis. However, reliable prognostic signatures based on aerobic glycolysis have not been well established.MethodsWe ...
Wei He, Xiang He, Enhui Li
doaj   +1 more source

Cancer-Secreted Exosomal MiR-620 Inhibits ESCC Aerobic Glycolysis via FOXM1/HER2 Pathway and Promotes Metastasis

Frontiers in Oncology, 2022
BackgroundEsophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate cell functions through exosomes.
Yanbo Zhu, Fang Li, Yilong Wan, Yilong Wan, Hansi Liang, Si Li, Bo Peng, Bo Peng, Liqun Shao, Liqun Shao, Yunyun Xu, Dong Jiang, Dong Jiang   +12 more
doaj   +1 more source

HPV E6/E7 promotes aerobic glycolysis in cervical cancer by regulating IGF2BP2 to stabilize m6A-MYC expression

International Journal on Biological Sciences, 2022
Enhanced aerobic glycolysis constitutes an additional source of energy for tumor proliferation and metastasis. Human papillomavirus (HPV) infection is the main cause of cervical cancer (CC); however, the associated molecular mechanisms remain poorly ...
Chenchen Hu, Tian Liu, C. Han, Yuxin Xuan, Dongbo Jiang, Yuanjie Sun, Xi-yang Zhang, Wenxin Zhang, Yiming Xu, Yang Liu, Jingyu Pan, Jing Wang, Jiang-li Fan, Yinggang Che, Yinan Huang, Jiaxing Zhang, Jiaqi Ding, Shuya Yang, Kun Yang   +18 more
semanticscholar   +1 more source

FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis

Cell Death and Disease, 2022
Although FOXD1 has been found to be involved in the malignant processes of several types of cancers, its role in pancreatic cancer (PC) is not well understood. This study aimed to investigate the expression and function of FOXD1 in PC.
K. Cai, Shiyu Chen, Changhao Zhu, Lin Li, Chao Yu, Zhiwei He, Chengyi Sun   +6 more
semanticscholar   +1 more source

mTOR regulates aerobic glycolysis through NEAT1 and nuclear paraspeckle-mediated mechanism in hepatocellular carcinoma

Theranostics, 2022
Background: Hepatocellular Carcinoma (HCC) is a major form of liver cancer and a leading cause of cancer-related death worldwide. New insights into HCC pathobiology and mechanism of drug actions are urgently needed to improve patient outcomes.
Hong Zhang, Xiaoyang Su, S. Burley, X. S. Zheng   +3 more
semanticscholar   +1 more source

Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms. [PDF]

PLoS ONE, 2014
Warburg effect, one of the hallmarks for cancer cells, is characterized by metabolic switch from mitochondrial oxidative phosphorylation to aerobic glycolysis.
Jia Liu, Ning Wu, Leina Ma, Ming Liu, Ge Liu, Yuyan Zhang, Xiukun Lin   +6 more
doaj   +1 more source

Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages

Frontiers in Immunology, 2022
Altered microenvironmental stiffness is a hallmark of inflammation. It is sensed by the mechanically activated cation channel Piezo1 in macrophages to induce subsequent immune responses.
Shaoqiu Leng, Xiaoyu Zhang, Shu-wen Wang, J. Qin, Qiang Liu, Anli Liu, Zi Sheng, Q. Feng, Xiang Hu, J. Peng   +9 more
semanticscholar   +1 more source

Brain aerobic glycolysis and resilience in Alzheimer disease

bioRxiv, 2022
The distribution of brain aerobic glycolysis (AG) in normal young adults correlates spatially with amyloid-beta (Aβ) deposition in individuals with dementia of the Alzheimer type (DAT) and asymptomatic individuals with brain amyloid deposition.
M. Goyal, Tyler M. Blazey, Nicholas V. Metcalf, M. McAvoy, Jeremy F. Strain, Maryam Rahmani, T. Durbin, C. Xiong, T. Benzinger, J. Morris, M. Raichle, Andrei G. Vlassenko   +11 more
semanticscholar   +1 more source

Curcumin Antagonizes Glucose Fluctuation-Induced Renal Injury by Inhibiting Aerobic Glycolysis via the miR-489/LDHA Pathway

Mediators of Inflammation, 2021
It has been considered that glucose fluctuation (GF) plays a role in renal injury and is related to diabetic nephropathy (DN) development. But the mechanism is still unclear. Aerobic glycolysis has become a topical issue in DN in recent years.
Xiaomei Fu, Jianfang Zhang, Xuanjie Huang, Zhifeng Mo, Ziyang Sang, Wenfei Duan, Wenfeng Huang   +6 more
doaj   +1 more source