Results 81 to 90 of about 339,203 (181)
STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
Nature Cell Biology, 2023 Liting Zhang +20 more
semanticscholar +1 more source
Unbounded solutions of models for glycolysis [PDF]
arXiv, 2020 The Selkov oscillator, a simple description of glycolysis, is a system of two ordinary differential equations with mass action kinetics. In previous work the authors established several properties of the solutions of this system. In the present paper we extend this to prove that this system has solutions which diverge to infinity in an oscillatory ...
arxiv
When Hopf meets saddle: bifurcations in the diffusive Selkov model for glycolysis [PDF]
arXiv, 2020 We study the linear instabilities and bifurcations in the Selkov model for glycolysis with diffusion. We show that this model has a zero wave-vector, finite frequency Hopf bifurcation to a growing oscillatory but spatially homogeneous state and a saddle-node bifurcation to a growing inhomogeneous state with a steady pattern with a finite wavevector. We
arxiv
Molecular Therapy: Oncolytics, 2020 Targeting metabolic reprogramming is an emerging strategy in cancer therapy. However, clinical attempts to target metabolic reprogramming have been proved to be challenging, with metabolic heterogeneity of cancer being one of many reasons that causes ...
Ting-Chun Kuo +10 more
doaj
Higher physical fitness levels are associated with less language decline in healthy ageing [PDF]
arXiv, 2018 Healthy ageing is associated with decline in cognitive abilities such as language. Aerobic fitness has been shown to ameliorate decline in some cognitive domains, but the potential benefits for language have not been examined. In a cross-sectional sample, we investigated the relationship between aerobic fitness and tip-of-the-tongue states.
arxiv
eLife, 2014 Aerobic glycolysis or the Warburg Effect (WE) is characterized by the increased metabolism of glucose to lactate. It remains unknown what quantitative changes to the activity of metabolism are necessary and sufficient for this phenotype.
Alexander A Shestov +10 more
doaj +1 more source
Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis
Frontiers in Oncology, 2020 Cellular metabolic reprogramming is now recognized as a hallmark of tumors. Altered tumor metabolism determines the malignant biological behaviors and phenotypes of cancer.
Lisi Ma, X. Zong
semanticscholar +1 more source
Journal of Functional Foods, 2019 Colorectal cancer (CRC) is an intractable intestinal tumor. Cancer cells prefer to aerobic glycolysis to meet the requirements of rapid proliferation.
Jiangying Shi +6 more
doaj
Assessing Performance of Aerobic Routines using Background Subtraction and Intersected Image Region [PDF]
arXiv, 2018 It is recommended for a novice to engage a trained and experience person, i.e., a coach before starting an unfamiliar aerobic or weight routine. The coach's task is to provide real-time feedbacks to ensure that the routine is performed in a correct manner. This greatly reduces the risk of injury and maximise physical gains.
arxiv
Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion [PDF]
arXiv, 2008 Tumour progression has been described as a sequence of traits or phenotypes that cells have to acquire if the neoplasm is to become an invasive and malignant cancer. Although the genetic mutations that lead to these phenotypes are random, the process by which some of these mutations become successful and spread is influenced by the tumour ...
arxiv