Results 91 to 100 of about 2,414,823 (352)
An affinity for affine quantum gravity [PDF]
Proceedings of the Steklov Institute of Mathematics, 2011 14 pages, contribution to the proceedings of the conference "Gauge Fields. Yesterday, Today, and Tomorrow", Moscow, Russia, Jan.
openaire +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Brazilian Archives of Biology and Technology, 2013 Catharacta maccormicki blood samples were collected in the winter (October) and in the summer (February) in order to study the intraerythrocytic organic phosphates, hemoglobin (Hb) electrophoretic patterns, oxygen blood equilibrium and stripped Hbs, as ...
Gustavo Fraga Landini +4 more
doaj +1 more source
Isotope shift on the chlorine electron affinity revisited by an MCHF/CI approach
, 2013 Today, the electron affinity is experimentally well known for most of the elements and is a useful guideline for developing ab initio computational methods.
Carette, Thomas, Godefroid, Michel
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Anion transport inhibitor binding to band 3 in red blood cell membranes. [PDF]
, 1983 The inhibitor of anion exchange 4,4'-dibenzoamido-2,2'-disulfonic stilbene (DBDS) binds to band 3, the anion transport protein in human red cell ghost membranes, and undergoes a large increase in fluorescence intensity when bound to band 3.
Dix, JA, Solomon, AK, Verkman, AS
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The affinity–efficacy problem: an essential part of pharmacology education
Royal Society Open ScienceA fundamental mistake in receptor theory has led to an enduring misunderstanding of how to estimate the affinity and efficacy of an agonist. These properties are inextricably linked and cannot be easily separated in any case where the binding of a ligand
James P. Higham, David Colquhoun
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S–V Semantic Affinity in Presentation Sentences with Preverbal Rhematic Subject
ELOPE, 2013 Firmly anchored in the Praguian theory of functional sentence perspective (FSP), the present paper discusses the prototypical type of sentences implementing the so–called Presentation Scale (i.e., that containing a rhematic subject in preverbal position)
Martin Adam
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