Simple Methods and Rational Design for Enhancing Aptamer Sensitivity and Specificity
Frontiers in Molecular Biosciences, 2018 Aptamers are structured nucleic acid molecules that can bind to their targets with high affinity and specificity. However, conventional SELEX (Systematic Evolution of Ligands by EXponential enrichment) methods may not necessarily produce aptamers of ...
Priya Kalra +6 more
doaj +1 more source
Molecular structure-affinity relationship of dietary flavonoids for bovine serum albumin [PDF]
, 2011 Jian Shi, Hui Cao
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Affine stacks (Champs affines)
, 2000 This is an expended and revised version of the preprint "Schematization of homotopy types". The purpose of this work is to introduce a notion of \emph{affine stacks}, which is a homotopy version of the notion of affine schemes, and to give several applications in the context of algebraic topology and algebraic geometry.
openaire +2 more sources
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Affine cellularity of affine Yokonuma–Hecke algebras [PDF]
Journal of Algebra, 2018 We give the details of the proofs of some ...
openaire +2 more sources
Rahner\u27s Primordial Words and Bernstein\u27s Metaphorical Leaps: The Affinity of Art with Religion and Theology [PDF]
, 2006 Karl Rahner\u27s notion of primordial words and Leonard Bernstein\u27s conception of music as intrinsically metaphorical are engaged to suggest that there is a fundamental affinity between artistic and religious imagination.
Masson, Robert
core +1 more source
Systemic Effects of Missense Mutations on SARS-CoV-2 Spike Glycoprotein Stability and Receptor Binding Affinity [PDF]
, 2020 Shaolei Teng +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Cloning of Plasmodium falciparum protein disulfide isomerase homologue by affinity purification using the antiplasmodial inhibitor 1,4‐bis{3‐[N‐(cyclohexyl methyl)amino]propyl}piperazine 1 [PDF]
, 2000 Isabelle Florent +7 more
openalex +1 more source