TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]
A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed +3 more
core +1 more source
Simple sequence repeats (SSRs) are important molecular markers for assessing genetic diversity in Arachis hypogaea L. and many other crops and constructing genetic linkage maps for important agricultural traits.
Houmiao Wang +9 more
doaj +1 more source
Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.
Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced liver cancer risk in 2016
Martin E Kimanya +5 more
doaj +1 more source
Determination of aflatoxin level in peanut using immunoaffinity column combined with ELISA
Peanut (Arachis hypogaea L.) is a largest source of edible oil in India, extensively consumed in the central and western parts of the country. The variability in the total aflatoxin and aflatoxin B1 levels in the different peanut samples collected was ...
Harish Chandra +4 more
doaj +1 more source
Dietary aflatoxin exposure of lactating mothers of children 0–6 months in Makueni County, Kenya
The southeastern region of Kenya is prone to aflatoxin outbreaks, yet maternal and infant aflatoxin intake levels remain unclear. We determined dietary aflatoxin exposure of 170 lactating mothers breastfeeding children aged 6 months and below in a ...
Isaac O. Ogallo +3 more
doaj +1 more source
Reducing child undernutrition through dietary diversification, reduced aflatoxin exposure, and improved hygiene practices: the immediate impacts in central Tanzania [PDF]
Open Access Article; Published online: 28 Nov 2019The study aimed to quantify the immediate effects of dietary diversification, food safety, and hygiene interventions on child undernutrition in four rural villages in Kongwa district of central Tanzania ...
Anitha, S. +11 more
core +1 more source
Background The adverse effect of aflatoxin in broilers is well known. However, dietary supplementation of Saccharomyces cell wall and/or Nanocurcumin may decrease the negative effect of aflatoxin B1 because of the bio-adsorbing feature of the functional ...
Aya Ashry +6 more
doaj +1 more source
Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study [PDF]
Fetal and early childhood environment, including the nutritional status of the pregnant mother and the infant, are considered critical for growth and risk of disease in later life.
Cardwell, K +6 more
core +3 more sources
Assessment of the Effect of Satureja montana and Origanum virens Essential Oils on Aspergillus flavus Growth and Aflatoxin Production at Different Water Activities [PDF]
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Aflatoxin ...
Garcia-Cela, Esther +5 more
core +5 more sources

