Results 51 to 60 of about 7,503 (205)

Platelet aggregometry testing during aspirin or clopidogrel treatment and measurement of clopidogrel metabolite concentrations in dogs with protein‐losing nephropathy

Journal of Veterinary Internal Medicine, 2020
Background Dogs with protein‐losing nephropathy (PLN) are treated with antiplatelet drugs for thromboprophylaxis but no standardized method exists to measure drug response.
Sarah Shropshire, Tyler Johnson, Christine Olver   +2 more
doaj   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Tailoring platelet inhibition according to multiple electrode aggregometry decreases the rate of thrombotic complications after intracranial flow-diverting stent implantation

, 2015
Background and purpose Pretreatment with dual antiaggregant drugs is accepted as a standard step in intracranial stent implantation. The aim of this study was to determine whether tailored antiaggregant medication based on platelet reactivity testing ...
Cinar, Celal, Korkmaz, Mehmet, Bozkaya, Halil, Oran, Ismail   +3 more
core   +1 more source

A correlation study between mean platelet volume and platelet aggregation study in acute coronary syndrome patients

Indian Journal of Pathology and Microbiology
Introduction: Platelets play an important role in cardiovascular disease mainly in the development of acute thrombotic events. Elevated platelet indices have been proposed as a risk factor for acute coronary syndrome (ACS).
PT Navya, M Natarajan
doaj   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source

Platelet aggregometry assay for evaluating the effects of platelet agonists and antiplatelet compounds on platelet function in vitro

MethodsX, 2019
Platelet aggregometry assays are generally used for the analysis of platelet function but can also be adapted for further research and therapy focused applications.
Alexandros Tsoupras, Ioannis Zabetakis, Ronan Lordan   +2 more
doaj   +1 more source

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

Correlation between multiple electrode aggregometry (MEA) with collagen as agonist and citrate or hirudin as anticoagulant.

, 2015
Correlation between multiple electrode aggregometry (MEA) with collagen as agonist and citrate or hirudin as anticoagulant.
Søs Neergaard-Petersen (447764), Steen Dalby Kristensen (447767), Anne-Mette Hvas (447765), Sanne Bøjet Larsen (447766), Morten Würtz (652804), Erik Lerkevang Grove (447768)   +5 more
core   +1 more source

Rosa rubiginosa L. Extract Rich in Bioactive Phenolics Possess Potent Anti‐Inflammatory, Antioxidant, Photoprotective, and Antimicrobial Biofunctional Activities

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
A rich in bioactive phenolics extract from Rosa rubiginosa L. exhibits strong antioxidant, photoprotective, anti‐inflammatory, and antimicrobial activities. Synergistic interactions among bioactives enhance efficacy, particularly against PAF‐mediated pathways.
Sophia Letsiou, Konstantina Kyratzi, Aliki Tsakni, Dimitrios Kranas, Konstantinos Pavlidis, Anna Ofrydopoulou, Panagiotis Halvatsiotis, Dimitra Houhoula, Alexandros Tsoupras   +8 more
wiley   +1 more source