Results 61 to 70 of about 7,503 (205)

Multiple electrode aggregometry as a method for platelet function assessment according to the European guidelines

, 2018
Platelets play an essential role in haemostasis. Assessment of their function is vital for anaesthesiologists evaluating haemostatic potential, especially during emergency operations.
Nicińska, Barbara; I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny, Pluta, Jan; I Department of Anaesthesiology and Intensive Care, Medical University of Warsaw, Trzebicki, Janusz; I Klinika Anestezjologii i Intensywnej Terapii, Warszawski Uniwersytet Medyczny   +2 more
core   +1 more source

Feasibility and comparability of different platelet function tests in acute stroke with or without prior antiplatelet therapy

Frontiers in Neurology
BackgroundThe clinical course of ischemic and hemorrhagic strokes can be influenced by the coagulation status of individual patients. The prior use of antiplatelet therapy (APT) such as acetylsalicylic acid (ASA) or P2Y12-antagonists has been ...
Jan Hendrik Schaefer, Franziska Lieschke, Hans Urban, Ferdinand O. Bohmann, Florian Gatzke, Wolfgang Miesbach   +5 more
doaj   +1 more source

Aggregometry detects platelet hyperreactivity in healthy individuals

Blood, 2005
AbstractAggregometry is widely used to assess platelet function, but its use in identifying platelet hyperreactivity is poorly defined. We studied platelet aggregation in 359 healthy individuals using the agonists adenosine diphosphate (ADP), epinephrine, collagen, collagen-related peptide, and ristocetin.
Donald L, Yee, Carol W, Sun, Angela L, Bergeron, Jing-Fei, Dong, Paul F, Bray   +4 more
openaire   +3 more sources

Evaluation of platelet function in thrombocytopenia

Platelets, 2018
Whole blood aggregometry is a functional assay for determination of platelet function. Until now, whole blood aggregometry has not been considered feasible at low platelet counts.
Mette Tiedemann Skipper, Peter Rubak, Jesper Stentoft, Anne-Mette Hvas, Ole Halfdan Larsen   +4 more
doaj   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, Volume 208, Issue 6, Page 1965-1979, June 2026.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

Postoperative bleeding in coronary artery bypass patients on double antiplatelet therapy: predictive value of preoperative aggregometry

, 2017
OBJECTIVES: We tested the possible value of routine aggregometry testing for bleeding prediction following coronary artery bypass grafting in patients who received preoperative double antiplatelet therapy.METHODS: In 226 patients undergoing on-pump ...
Bifulco, Olimpia, Spadafora, Andrea, Andrea Spadafora, Borrelli, Margherita, Nicola Galdieri, Olimpia Bifulco, Sergio Nappo Quintiliano, Quintiliano, Sergio Nappo, Margherita Borrelli, Alessandro Della Corte, Della Corte, Alessandro, Bancone, Ciro, Galdieri, Nicola, Marisa De Feo, de Feo, Marisa, Ciro Bancone   +15 more
core   +1 more source

Differences in platelet aggregation using whole blood impedance aggregometry in experimental groups.

, 2015
ADP = adenosine diphosphate; AA = arachidonic acid; A.U.C = area under the curve; a.u. = arbitrary unitsDifferences in platelet aggregation using whole blood impedance aggregometry in experimental groups.
Jin Won Kim (224828), Charles P. Lin (392128), Peter K. Henke (697745), Farouc A. Jaffer (697749), Ronan J. P. Margey (697748), Peter Libby (372665), Jason R. McCarthy (273236), Chase W. Kessinger (470740), Brian Thompson (169977), Martin Sillesen (697747), Tetsuya Hara (697746), Ralph Weissleder (60)   +11 more
core   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, Volume 115, Issue 5, Page 1015-1024, May 2026.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

Platelet reactivity clinical and biochemical markers when taking acetylsalicylic acid as part of dual antiplatelet therapy in the myocardial infarction subacute period

Рациональная фармакотерапия в кардиологии
Aim. To study markers that determine residual platelet reactivity in the subacute period of myocardial infarction (MI) during the administration of acetylsalicylic acid (ASA) as part of dual antiplatelet therapy.Material and methods. 405 patients with MI
T. P. Pronko, V. A. Snezhitskiy, A. V. Kapytski   +2 more
doaj   +1 more source

Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant in pseudothrombocytopenia

Platelets, 2020
MgSO4 is effective in preventing spontaneous in vitro platelet agglutination in anticoagulant-induced pseudothrombocytopenia (PTCP). In order to learn more about its potential as an in vitro anticoagulant, platelets from MgSO4-anticoagulated blood were ...
Steffen Mannuß, Peter Schuff-Werner, Katrin Dreißiger, Christine Burstein   +3 more
doaj   +1 more source