Results 71 to 80 of about 7,503 (205)
Platelet clotting defects in severe trauma identified by a whole blood microfluidic assay
Abstract Background Hemorrhage is the leading cause of preventable death in severe trauma, with primary hemostasis relying on platelet‐rich clot formation under high shear flow. This study quantifies the incidence, severity, and heterogeneity of platelet dysfunction in Level I trauma patients.
Gian Rivera Crespo +4 more
wiley +1 more source
Stent Thrombosis: A Narrative Review From Pathophysiology to Therapy
Stent thrombosis remains a life‐threatening complication of PCI driven by complex interactions between stent design, procedural factors, thrombogenic milieu, and inflammation. This review integrates pathophysiological mechanisms with contemporary and emerging therapeutic strategies, highlighting optimized PCI, tailored antithrombotic therapy, and novel
Emanuele Cecchi +8 more
wiley +1 more source
Correlation between VerifyNow and multiple electrode aggregometry (MEA) using arachidonic acid (AA) as agonist and hirudin as anticoagulant.
Søs Neergaard-Petersen (447764) +5 more
core +1 more source
Introduction Light transmission aggregometry (LTA), used to detect clopidogrel resistance in patients under antiplatelet therapy, is prone to multiple variables potentially influencing results and interpretation.
Ron H.N. van Schaik +11 more
core +1 more source
Correlation between multiple electrode aggregometry (MEA) with arachidonic acid (AA) as agonist and citrate or hirudin as anticoagulant.
Søs Neergaard-Petersen (447764) +5 more
core +1 more source
Viscoelastic Testing for Coagulation Management in Vascular Surgery—A Narrative Review
ABSTRACT Background Viscoelastic testing (VET) has been increasingly used in cardiac, trauma, and hepatic surgery where it helps tackle the development of complex coagulopathies. Despite this, data on using VETs in vascular surgery remains limited to small and non‐randomised control studies. Although the improvement in vascular techniques has decreased
Alexandru Munteanu, Elena Bax
wiley +1 more source
Abstract Background Whole blood (WB) transfusions are being reevaluated because of their high hemostatic capacity and reduced volume. Fibrinogen γ‐chain peptide‐coated, adenosine 5′‐diphosphate (ADP)‐encapsulated liposomes are potent hemostatic adjuvants promoting platelet thrombi formation.
Osamu Ishida +6 more
wiley +1 more source
Correlation between VerifyNow and multiple electrode aggregometry (MEA) using arachidonic acid (AA) as agonist and citrate as anticoagulant.
Søs Neergaard-Petersen (447764) +5 more
core +1 more source
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay +4 more
wiley +1 more source
Antiplatelet drugs play a pivotal role in the management of patients with acute coronary syndrome. Clopidogrel is an important antiplatelet drug commonly used in the treatment of those patients. However, the variability in patient response to clopidogrel
John I. Louca +3 more
doaj +1 more source

