Results 91 to 100 of about 211,860 (282)

GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging

Experimental and Molecular Medicine, 2018
Aging: Clues in nuclear proteins Abnormal versions of proteins that support the structure and function of the membrane of the cell nucleus are implicated in premature aging disorders, and also in normal aging.
Jin Young Lee, Kyung-Rok Yu, Byung-Chul Lee, Insung Kang, Jae-Jun Kim, Eui-Jung Jung, Hyung-Sik Kim, Yoojin Seo, Soon Won Choi, Kyung-Sun Kang   +9 more
doaj   +1 more source

Effect of training on improving swimming biological age and capabilities of people aged 30-35 years

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2014
Purpose: to verify the anti-aging effect of improving navigation on involution processes of the human body 30-35. Material: participation in the experiment took 43 men and women aged 30-35 years. Biological age is measured by the method of V.P. Voytenko.
N.V. Fedinyak
doaj   +1 more source

Cellular senescence - its role in cancer and the response to ionizing radiation [PDF]

, 2011
© 2011 Sabin and Anderson; licensee BioMed Central Ltd. This article is available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http ...
Anderson, RM, Sabin, RJ
core   +2 more sources

Analysis of Temperature and Stress Distribution on the Bond Properties of Hybrid Tailored Formed Components

Advanced Engineering Materials, EarlyView.
Hybrid materials enable high‐performance components but are challenging to process. This study explores an inductive heating concept with spray cooling for steel–aluminum specimens in a two‐step process including friction welding and cup backward extrusion.
Armin Piwek, Eduard Ortlieb, Caner‐Veli Ince, Julius Peddinghaus, Hendrik Wester, Johanna Uhe, Annika Raatz, Kai Brunotte   +7 more
wiley   +1 more source

CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease [PDF]

, 2017
Patients with chronic kidney disease (CKD) display a progeric vascular phenotype linked to apoptosis, cellular senescence and osteogenic transformation. This has proven intractable to modelling appropriately in model organisms.
Bárány, Peter, Luttropp, Karin, McGuinness, Dagmara, Nordfors, Louise, Olauson, Hannes, Qureshi, Abdul Rashid, Ripsweden, Jonaz, Schalling, Martin, Shiels, Paul G., Stenvinkel, Peter, Söderberg, Magnus, Wennberg, Lars, Wernerson, Annika, Witasp, Anna   +13 more
core   +1 more source

Influence of a Standard Heat Treatment on the Microstructure and Properties of Inconel X‐750 Produced by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Ni‐base superalloys produced using additive manufacturing (AM) have a different response to heat treatments when compared to their conventional counterparts. Due to such unpredictability, various alloys with industrial interest are currently overlooked in most prior AM research.
Guilherme Maziero Volpato, Adriano de Souza Pinto Pereira, Steffen Neumeier, Dachamir Hotza, Mathias Göken, Ulrich Tetzlaff, Márcio Celso Fredel   +6 more
wiley   +1 more source

Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging

Stem Cell Reports, 2014
Werner syndrome (WS) patients exhibit premature aging predominantly in mesenchyme-derived tissues, but not in neural lineages, a consequence of telomere dysfunction and accelerated senescence.
Hoi-Hung Cheung, Xiaozhuo Liu, Lucile Canterel-Thouennon, Lu Li, Catherine Edmonson, Owen M. Rennert   +5 more
doaj   +1 more source

Microstructural and Mechanical Properties of a Hard Anodic Coating Applied on an Elastically Prestrained Aluminum Substrate

Advanced Engineering Materials, EarlyView.
Prestraining the substrate influences coating formation process. Higher prestraining force leads to higher coating thickness and lower hardness. Increase in prestraining force enhances preliminary damage in hard anodic coating. Fatigue damage mechanisms change for hard anodized prestrained samples.
Linto George Thomas, Lisa Winter, Frank Simchen, Tobias Breitfeld, Thomas Lampke   +4 more
wiley   +1 more source

Alterations to nuclear architecture and genome behavior in senescent cells. [PDF]

, 2007
The organization of the genome within interphase nuclei, and how it interacts with nuclear structures is important for the regulation of nuclear functions.
Abney J.R., Agrelo R., Barboro P., Becker P.B., Bemiller P.M., Benn P.A., Berezney R., Bowman P.D., Bridger J.M., Bridger J.M., C. S. CLEMENTS, Campisi J., Chaly N., Chang K.S., Cremer T., de Lange T., Dell'Orco R.T., Dijkwel P.A., Ferbeyre G., Filesi I., Fisher A.G., Fleischer S., Goldman R.D., Gruenbaum Y., Haque F., Hernandez-Verdun D., Holliday R., Hozak P., I. R. KILL, I. S. MEHTA, J. M. BRIDGER, Kill I.R., Kreth G., Lezhava T., Li Y., M. FIGGITT, Mallette F.A., Manuelidis L., Mazin A.L., Mitsui Y., Mukherjee A.B., Nickerson J., Okabe J., Padiath Q.S., Pawelec G., Petrova N.V., Schardin M., Schulz L., Smilenov L.B., Strouboulis J., Tanabe H., van Driel R., Wang G.S.   +52 more
core   +1 more source

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source