Results 171 to 180 of about 211,860 (282)

Unraveling immunosenescence in sepsis: from cellular mechanisms to therapeutics. [PDF]

Cell Death Dis
Wang Y, Zhang H, Miao C.
europepmc   +1 more source

Bi‐Functional Diaminopropane Additive Enables Stable Li Anodes and Highly Efficient Cathodes for High‐Performance Li‐Air Batteries

Advanced Science, EarlyView.
Diaminopropane (DAP) solvent is employed as a bi‐functional additive for Li‐air batteries. It spontaneously reacts to form a gel layer to prevent corrosion on the Li anode and maintain a liquid state at the cathode to improve the decomposition of Li2O2.
Honghao Hu, Qingxu Zhang, Jiucong Liu, Junjie Li, Pingli Wu, Caicai Li, Peipei Du, Huiqiao Li, Xizheng Liu   +8 more
wiley   +1 more source

Ovarian Endometriosis Accelerates Premature Ovarian Failure and Contributes to Osteoporosis and Cognitive Decline in Aging Mice. [PDF]

Int J Mol Sci
Ge L, Yang Y, Xiao T, Gao Y, Chang W, Du F, Yu M, Zhang JV.   +7 more
europepmc   +1 more source

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

Advanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu, Yu Liu, Junheng Zhang, Shuang Yang, Tianming Li, Haiqian Huang, Qian Liu, Hengliang Wang, Li Cao, Zhenghua An, Min Li, Hua Wang   +11 more
wiley   +1 more source

Endoscopic characterization of oropharyngeal dysphagia in patients with dementia. [PDF]

Front Aging
Peranovic S, Pourhassan M, Labeit B, Muhle P, Suntrup-Krueger S, Warnecke T, Dziewas R, Trampisch U, Wirth R, Lueg G.   +9 more
europepmc   +1 more source

Engineering Adenine Deaminase TadA for Precise and PAM‐Flexible Point Mutagenesis and Gradient‐Tuning Endogenous Protein Design

Advanced Science, EarlyView.
Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun, Si Cheng, Nan Chai, Jianing Mi, Ruixiang Zhang, Qian Qian, Zhiye Zheng, Ke Chen, Dongchang Zeng, Xin Peng, Mengyuan Shen, Degui Zhou, Qinlong Zhu, Qi Liu, Jiantao Tan   +14 more
wiley   +1 more source

Gray Hair: From Preventive to Treatment. [PDF]

Clin Cosmet Investig Dermatol
Herdiana Y.
europepmc   +1 more source

A Study of Skeletal Stem Cell Dynamics and Its Potential Applications in the Design of a Titanium Implant for Senile Osteoporosis

Advanced Science, EarlyView.
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan, Tao Zheng, Mingsong Mao, Pengfei Gao, Yulu Yang, Rong Wang, Yao Yang, Yangpeng Zuo, Tiantian Yuan, Ruqing Bai, Weihu Yang, Xingchen Yan, Kaiyong Cai   +12 more
wiley   +1 more source

Bioinformatic and genomic analysis identifies C allele of APOE rs7412 as the most prominent variant limiting extreme human longevity. [PDF]

Sci Rep
Satria RD, Sukorini U, Lesmana MHS, Muhammad Irham L, Adikusuma W, Rahmawati H, Harahap NIF, Rinastiti P, Wardhana DA, Sianipar O, Ninggar GAW, Sofro ZM, Budi NYP, Nanda JD, Hasan F, Rahardjo TBW, Lin CF.   +16 more
europepmc   +1 more source

Innovative Design of PEI‐Modified AMO‐Layered Double Hydroxide for Efficient and Stable Direct Air Capture of CO2

Advanced Science, EarlyView.
An uncalcined, hydroxyl‐rich MgAl layered double hydroxide, synthesized via low‐energy aqueous miscible organic solvent treatment, enables mesopore‐engineered polyethyleneimine anchoring for direct air capture (DAC). The exfoliated structure exposes abundant hydroxyls that stabilize amines via hydrogen bonding, effectively suppressing oxidative ...
Meng Zhao, Liang Huang, Yanshan Gao, Ziling Wang, Xuancan Zhu, Qiang Wang, Dermot O'Hare   +6 more
wiley   +1 more source