Results 61 to 70 of about 722,561 (200)
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Mammalian comparative sequence analysis of the Agrp locus. [PDF]
PLoS ONE, 2007 Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance.
Christopher B Kaelin +3 more
doaj +1 more source
Integrative Zoology, EarlyView.Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2015 Background and Objective: Diabetes mellitus is the most common type of metabolic diseases which is characterized with hyperglycemia due to implicit or relative insulin deficiency. Diabetes mellitus is acutely related to obesity.
Ghiasi E +3 more
doaj
The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. [PDF]
PLoS ONE, 2017 Melanin pigmentation patterns are ubiquitous in animals and function in crypsis, physical protection, thermoregulation and signalling. In vertebrates, pigmentation patterns formed over large body regions as well as within appendages (hair/feathers) may ...
Thanh-Lan Gluckman, Nicholas I Mundy
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang +2 more
wiley +1 more source
Middle East Current PsychiatryBackground Appetite regulation involves a complex interplay between peripheral signals and central hypothalamic neuropeptides. Two key hormones in this mechanism are leptin, an adipocyte-derived hormone that suppresses food intake, and Agouti-Related ...
Nehal Mostafa +3 more
doaj +1 more source
Nutrición Hospitalaria, 2014 The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents. Background & Aims: The role of diet glycemic index (GI) in the control of orexigenic and anorexigenic factors of the energy ...
Bárbara Dal Molin Netto +9 more
doaj +1 more source