Results 111 to 120 of about 98,913 (262)

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Recombinant expression of functional mouse AhR LBD in E. coli [PDF]

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic halogenated aromatic hydrocarbon, which is a potent toxin to different species such as fish, birds, and mammalians.
Elhawari, Wail
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Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα

, 2018
Isopsoralen (IPRN), one of the main effective ingredients in Psoralea corylifolia Linn, has a variety of biological effects, including antiosteoporotic effects.
Kai Cheng, Luna Ge, Yazhou Cui, Jinxiang Han   +3 more
core   +1 more source

CD248/Endosialin Regulates Synovial Fibroblast State to Control Coupling of Inflammation and Bone Damage in Murine Models of Immune‐Mediated Inflammatory Arthritis and Aging

Arthritis &Rheumatology, EarlyView.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/endosialin is expressed by fibroblasts in the synovium, is highly up‐regulated during inflammation, and has been proposed as a potential therapeutic target.
Samuel Kemble, Corinna Wehmeyer, James M. Brown, Charlotte G. Smith, Holly R. Adams, Eva Crombie, Ellie Northall, Maryam Imran, Paulynn Chin, Harris R. Perlman, Christopher D. Buckley, Adam P. Croft, Amy J. Naylor   +12 more
wiley   +1 more source

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

, 2016
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor; the AhR Per-AhR/Arnt-Sim (PAS) domain binds ligands. We developed homology models of the AhR PAS domain to characterize previously observed intra- and interspecies ...
Sammy M. Khalil (2348380), Daniel C. Koch (315796), William H. Bisson (189115), Edmond F. O’Donnell (315794), Siva Kumar Kolluri (315800), Nancy I. Kerkvliet (315799), Ruben Abagyan (220938), Robert L. Tanguay (127737)   +7 more
core   +1 more source

Higher risk of Long COVID among patients with autoimmune rheumatic diseases and immunomodulatory therapy: a retrospective cohort analysis of national US data.

Arthritis &Rheumatology, Accepted Article.
Background Little is known about the prevalence of and factors associated with Long COVID in patients with autoimmune rheumatic diseases (AIRDs). Methods We conducted a retrospective cohort study using data from the National Clinical Cohort Collaborative (N3C).
Namrata Singh, A. Jerrod Anzalone, Holland Stevenson, Londyn Robinson, Lesley E. Jackson, Sandra E. Safo, Zachary Butzin‐Dozier, Kaleb Michaud, Maria I. Danila, Jasvinder A. Singh, Rena C. Patel, on behalf of the National Clinical Cohort Collaborative (N3C) Consortium   +11 more
wiley   +1 more source

Design of azine antioxidants for sustainable biodiesel: integrating structural characterization and molecular modeling

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing global demand for sustainable energy solutions has intensified the search for renewable alternatives to fossil fuels, with biodiesel emerging as a promising candidate due to its biodegradability and lower emissions. However, its large‐scale application is limited by low oxidative stability, which compromises storage and performance.
Patricia R. S. Wenceslau, Chris H. J. Franco, Leonardo R. de Almeida, Vitor S. Duarte, Ronaldo G. F. Junior, Guilherme Paixão, Antônio S. N. Aguiar, Gilberto L. B. de Aquino, Leonardo G. Costa, Leonardo L. Borges, Hamilton B. Napolitano   +10 more
wiley   +1 more source

The OKR of AhR−/− mice is decreased.

, 2013
(A) Example of eye movements evoked in both AhR+/+ and AhR−/− mice in horizontal position (EHp) during a rotation at 5°/sec in light in counter-clockwise. (B) OKR gain at 5°/sec.
Antoine Mialot (105606), Pedro Fernandez-Salguero (105608), Jean-Maurice Petit (105607), Mathieu Beraneck (105613), Aline Chevallier (105605), Robert Barouki (105609), Xavier Coumoul (9804)   +6 more
core   +1 more source

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Design and production of stable mutants of the PAS-B domain of the transcription factor AhR (Aryl hydrocarbon Receptor)

reservedIl recettore citoplasmatico AhR (aryl hydrocarbon receptor) appartenente alla famiglia di fattori di trascrizione bHLH-PAS è in grado di modulare diverse risposte in base ai diversi stimoli ambientali a cui è sottoposto.
LAUDATO, GLORIA
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