Results 161 to 170 of about 98,913 (262)

Aryl Hydrocarbon Receptor Deficiency Impairs Intestinal Barrier Development, While 2'-Fucosyllactose Reduces Paracellular Permeability in Caco-2 Cells. [PDF]

Toxins (Basel)
Madella AM, van Gerven CCE, Sendino Garví E, van Bergenhenegouwen J, Garssen J, Masereeuw R, Overbeek SA.   +6 more
europepmc   +1 more source

Solving the Capacitated Arc Routing Problem Using Logic‐Based Benders Decomposition

Networks, EarlyView.
ABSTRACT In this paper, we present a new exact algorithm for solving the capacitated arc routing problem using logic‐based benders decomposition. The master problem is formulated based on variables that measure the number of deadheadings of each edge. These variables have been converted into binary form, which enables the use of both new and stronger ...
Alexander Ingemann Lindhardt, Sanne Wøhlk, Michael M. Sørensen   +2 more
wiley   +1 more source

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Microbiome-Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease. [PDF]

Microbiologyopen
Mahdiabadi MA, Moghaddam A, Erfanian N.
europepmc   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

The aryl hydrocarbon receptor and kynurenine pathway: connecting inflammatory bowel disease and depression via the microbiota gut brain axis. [PDF]

Front Neurosci
Bogdon R, Roark K, Busbee PB.
europepmc   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, EarlyView.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

A helminth-microbiota metabolic relay promotes disease tolerance. [PDF]

Gut Microbes
Sun R, Liu Y, Wang Y, Xu N, Ma X, Lv Q, Zhao X, Boireau P, Wu Z, Liu M, Liu X, Jin X.   +11 more
europepmc   +1 more source

Linear System Identification and Control of a Low‐Cost High‐Performance Omnidirectional Marine Surface Vehicle for Swarming Applications

Journal of Field Robotics, EarlyView.
ABSTRACT Marine operations traditionally rely on human intervention, a costly and disruptive method. Autonomous surface vehicles (ASVs) offer a powerful alternative, capable of operating autonomously, for extended periods, and with various sensors for various missions.
Ayman El Qemmah, Gianni Cario, Alessandro Casavola, Marco Lupia, Francesco Tedesco   +4 more
wiley   +1 more source