Systemic Immunosuppression to Reduce Surgical Intervention in ANCA‐Negative Subglottic Stenosis
Idiopathic subglottic stenosis (iSGS) typically follows an indolent course managed with surgical dilatation, though a subset demonstrates aggressive, recurrent disease. In this retrospective cohort study, systemic immunosuppression significantly prolonged inter‐dilation intervals in both granulomatosis with polyangiitis‐associated SGS and an “atypical”
Guy Benshetrit +5 more
wiley +1 more source
Transcriptomic and functional responses of the cystic fibrosis airway epithelium to CFTR modulator therapy. [PDF]
Vladar EK +15 more
europepmc +1 more source
Socioeconomic Deprivation and Vocal Handicap in Adults With Voice Disorders
This study examined the relationship between socioeconomic deprivation and quality of life as measured by the Voice Handicap Index (VHI) in adults with voice disorders. Patients living with socioeconomic deprivation experienced greater voice‐related handicap from voice disorders than those from more affluent backgrounds, even when controlling for ...
Robert Brinton Fujiki +1 more
wiley +1 more source
<i>Klebsiella pneumoniae</i> infection induces an S100A8/A9-mediated autocrine loop in human airway epithelium to amplify inflammation. [PDF]
Zheng J +5 more
europepmc +1 more source
The Laryngeal Auditory Startle Reflex (LASR): A New Component of the Auditory Startle Response
The auditory startle reflex contains a distinct laryngeal component, termed the laryngeal auditory startle reflex (LASR). In healthy adults, the LASR is modulated by supratentorial influences and habituates to repetitive stimuli. Physiologic and pathologic implications for the LASR as a component of the overall human SR remain to be determined but may ...
Catherine F. Sinclair +4 more
wiley +1 more source
Untargeted Metabolomics of Human Airway Epithelium Reveals Neuroactive Signatures Linked to Pulmonary Neuroendocrine Cell Enrichment and Allergen Exposure. [PDF]
Mann-Nüttel R, Diya A, Forsythe P.
europepmc +1 more source
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Next Decade Research in Asthma: Broad Omics-Based Exploration Versus Targeted Airway Epithelium Studies. [PDF]
Picado C +3 more
europepmc +1 more source
Abstract Background In individuals with cystic fibrosis (CF), lean mass and muscle strength are important predictors of clinical outcomes. This study evaluated associations among body composition, handgrip strength, muscle quality, physical activity, and health‐related quality of life in CF. Methods This observational, cross‐sectional study included 27
Benjamin H. Crain +9 more
wiley +1 more source
Mitochondrial targeting by measles virus nucleoprotein modulates viral spread in human airway epithelium. [PDF]
Durnell-Bettis LA +9 more
europepmc +1 more source

