Results 221 to 230 of about 614,051 (372)

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

open access: yesAdvanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan   +12 more
wiley   +1 more source

Utilising feed effectors and automated feeders for semi‐intensive pacific white shrimp (Litopenaeus vannamei) production

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 540-551, December 2022., 2022
Abstract Feed effectors have been suggested to improve the efficiency of plant‐based shrimp diets by increasing attractability and palatability. This research trial aimed to expand upon previous Pacific white shrimp (Litopenaeus vannamei) research involving plant‐based diets, feed effectors and passive acoustic monitoring (PAM) in a laboratory setting ...
Samuel Walsh   +4 more
wiley   +1 more source

Regional quantification of metabolic liver function using hyperpolarized [1-<sup>13</sup>C] pyruvate MRI. [PDF]

open access: yesSci Rep
Kjaergaard U   +13 more
europepmc   +1 more source

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

open access: yesAdvanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li   +8 more
wiley   +1 more source

Radiolysis of Solid L-α-Alanine [PDF]

open access: bronze, 1967
Atsuko Minegishi   +2 more
openalex   +1 more source

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

open access: yesAdvanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng   +13 more
wiley   +1 more source

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