Results 111 to 120 of about 96,578 (258)

Decreased endogenous nitric oxide production in acute decompensated heart failure with a reduced ejection fraction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Heart failure represents a substantial burden to both patients and healthcare systems worldwide. Nitric oxide (NO) dysregulation may play a key role in patients transitioning from chronic to acute heart failure with a reduced ejection fraction (HFrEF). Plasma nitrite (NO2−) is highly reflective of local nitric oxide production and has not
Roman Falls   +3 more
wiley   +1 more source

Identification of hub biomarkers and exploring the roles of immunity, M6A, ferroptosis, or cuproptosis in rats with diabetic erectile dysfunction

open access: yesAndrology, Volume 11, Issue 2, Page 316-331, February 2023., 2023
Abstract Background Currently, patients with diabetic erectile dysfunction (DMED) were not satisfied with the effects of first‐line phosphodiesterase type 5 inhibitors (PDE5Is). Hence, this paper was designed to mine hub biomarkers in DMED and explore its potential mechanisms.
Yi Wang   +4 more
wiley   +1 more source

Impact of immigration on outcomes following acute decompensated heart failure: A retrospective cohort study

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The study aims to investigate the impact of immigration status on short‐ and long‐term outcomes in patients hospitalized with acute decompensated heart failure (ADHF). Methods We conducted a retrospective cohort study at a single centre, analysing 7457 patients admitted for ADHF between 2007 and 2017, with follow‐up until 2020 (mean 3.7 ± 
Gil Marcus   +9 more
wiley   +1 more source

Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Information about current use of finerenone in patients with heart failure (HF) finerenone in clinical practice is scarce, and its effectiveness in clinical practice in patients is scarce. We aim to assess both the baseline clinical profile and prognostic role of finerenone in patients with HF, irrespective of ejection fraction.
Gonzalo Luis Alonso Salinas   +32 more
wiley   +1 more source

Moderate hyperuricaemia ameliorated kidney damage in a low‐renin model of experimental renal insufficiency

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 21-32, January 2023., 2023
Abstract Uric acid has promoted renal fibrosis and inflammation in experimental studies, but some studies have shown nephroprotective effects due to alleviated oxidative stress. We studied the influence of experimental hyperuricaemia in surgically 5/6 nephrectomized rats. Three weeks after subtotal nephrectomy or sham operation, the rats were allocated
Venla Kurra   +9 more
wiley   +1 more source

Effect of Aldosterone Antagonist (SC 9420) on Periodic Paralysis [PDF]

open access: bronze, 1962
Shigeo Okinaka   +8 more
openalex   +1 more source

A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry

open access: yesESC Heart Failure, EarlyView.
The H2‐Registry: overview, first results and outlook. Abstract Aims Heart failure (HF) is a highly prevalent condition affecting 1–3% of the adult population in Europe. Despite landmark improvements in HF care over the last two decades, hospitalization and mortality rates remain relatively high.
Johannes Leiner   +15 more
wiley   +1 more source

THE EFFECT OF CORTICOSTEROID INJECTION ON ALDOSTERONE SECRETION1

open access: bronze, 1956
Gordon Farrell   +2 more
openalex   +1 more source

Early diuretic response and outcome prediction in ambulatory worsening heart failure: Natriuresis versus diuresis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Early diuresis and natriuresis are commonly used to assess the efficacy of decongestive therapy following an acute heart failure episode. There is limited knowledge regarding which parameter better predicts adverse clinical outcomes, especially in the outpatient setting.
M. Cobo Marcos   +15 more
wiley   +1 more source

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