Results 11 to 20 of about 223,635 (302)

Aldosterone is a possible new stimulating factor for promoting vascular calcification

open access: yesFrontiers in Bioscience-Landmark, 2021
Background: Aldosterone is an important hormone in the renin-angiotensin-aldosterone system (RAAS), and playing a pivotal role in the development of hypertension, heart failure, and other cardiovascular diseases.
Xusheng Zhang   +6 more
doaj   +1 more source

Comparison of the Chemiluminescence Immunoassay LIAISON® with the Radioimmunoassay for Aldosterone and Renin Measurement

open access: yesPrague Medical Report, 2021
Determination of renin plasma levels is useful in the diagnosis of hypertension and in the therapeutic follow-up of hypertensive patients. Plasmatic concentration of renin decreases in patients with hypertension due to a primary hyperaldosteronism ...
Jana Uhrová   +3 more
doaj   +1 more source

G protein–coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension

open access: yesFrontiers in Endocrinology, 2023
Aldosterone is one of the most essential hormones synthesized by the adrenal gland because it regulates water and electrolyte balance. G protein–coupled estrogen receptor (GPER) is a newly discovered aldosterone receptor, which is proposed to mediate the
Xuehan Li   +11 more
doaj   +1 more source

Aldosterone Decreases Vasopressin-Stimulated Water Reabsorption in Rat Inner Medullary Collecting Ducts

open access: yesCells, 2020
Aldosterone indirectly regulates water reabsorption in the distal tubule by regulating sodium reabsorption. However, the direct effect of aldosterone on vasopressin-regulated water and urea permeability in the rat inner medullary collecting duct (IMCD ...
Yanhua Wang   +4 more
doaj   +1 more source

Pathology and gene mutations of aldosterone-producing lesions

open access: yesEndocrine Journal, 2023
The human adrenal cortex secretes aldosterone and cortisol as major corticosteroids. For their production, CYP11B2 and CYP11B1 catalyze the last steps in the syntheses of aldosterone and cortisol, respectively.
Koshiro Nishimoto   +4 more
doaj   +1 more source

Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension

open access: yesFrontiers in Endocrinology, 2021
Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension. It can be caused by the overproduction of aldosterone in one or both adrenal glands. The most common subtypes of PA are unilateral aldosterone over-production
Fatin Athirah Pauzi, Elena Aisha Azizan
doaj   +1 more source

Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. [PDF]

open access: yesPLoS ONE, 2014
Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis.To investigate whether aldosterone induces galectin-3 secretion
Yen-Hung Lin   +11 more
doaj   +1 more source

Aldosterone Excess Induced Mitochondria Decrease and Dysfunction via Mineralocorticoid Receptor and Oxidative Stress In Vitro and In Vivo

open access: yesBiomedicines, 2021
Aldosterone excess plays a major role in the progression of cardiac dysfunction and remodeling in clinical diseases such as primary aldosteronism and heart failure. However, the effect of aldosterone excess on cardiac mitochondria is unclear.
Cheng-Hsuan Tsai   +12 more
doaj   +1 more source

Body mass index predicts aldosterone production in hypertensive postmenopausal women

open access: yesClinical and Experimental Hypertension, 2020
Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic. Related works have shown exciting results on the effects of various conditions on aldosterone content, but the correlation between ...
Lijun Li   +3 more
doaj   +1 more source

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

open access: yes, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C.   +8 more
core   +1 more source

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