Results 11 to 20 of about 232,884 (341)
Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure [PDF]
Aims Activation of the renin-angiotensin-aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Anker, Stefan D.+17 more
core +5 more sources
Adipocytes, aldosterone and obesity-related hypertension [PDF]
Understanding the mechanisms linking obesity with hypertension is important in the current obesity epidemic as it may improve therapeutic interventions.
Friederich-Persson, Malou+3 more
core +2 more sources
Intratumoural aldosterone and CYP11B2 expression levels among different genotypes of aldosterone producing tumours. [PDF]
Primary aldosteronism is the most common endocrine cause of hypertension, affecting 5–10% of hypertensive patients. Determining the source of aldosteronism is necessary for correct diagnosis and further molecular analysis. To investigate the relationship
Åkerström T+4 more
europepmc +2 more sources
Aldosterone is a possible new stimulating factor for promoting vascular calcification
Background: Aldosterone is an important hormone in the renin-angiotensin-aldosterone system (RAAS), and playing a pivotal role in the development of hypertension, heart failure, and other cardiovascular diseases.
Xusheng Zhang+6 more
doaj +1 more source
Aldosterone as a Mediator of Cardiovascular Damage.
Besides the physiological regulation of water, sodium, and potassium homeostasis, aldosterone modulates several physiological and pathological processes in the cardiovascular system.
F. Buffolo+3 more
semanticscholar +1 more source
Aldosterone is one of the most essential hormones synthesized by the adrenal gland because it regulates water and electrolyte balance. G protein–coupled estrogen receptor (GPER) is a newly discovered aldosterone receptor, which is proposed to mediate the
Xuehan Li+11 more
doaj +1 more source
Determination of renin plasma levels is useful in the diagnosis of hypertension and in the therapeutic follow-up of hypertensive patients. Plasmatic concentration of renin decreases in patients with hypertension due to a primary hyperaldosteronism ...
Jana Uhrová+3 more
doaj +1 more source
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain.
M. Vaduganathan+5 more
semanticscholar +1 more source
Aldosterone indirectly regulates water reabsorption in the distal tubule by regulating sodium reabsorption. However, the direct effect of aldosterone on vasopressin-regulated water and urea permeability in the rat inner medullary collecting duct (IMCD ...
Yanhua Wang+4 more
doaj +1 more source
Pathology and gene mutations of aldosterone-producing lesions
The human adrenal cortex secretes aldosterone and cortisol as major corticosteroids. For their production, CYP11B2 and CYP11B1 catalyze the last steps in the syntheses of aldosterone and cortisol, respectively.
Koshiro Nishimoto+4 more
doaj +1 more source