Results 41 to 50 of about 4,200 (201)
Pharmaceuticals, 2011 In the published version “Paladini et al. reported that aliskiren 300 mg provided a sustained BP-lowering effect beyond the 24-h dosing interval, with a significantly smaller loss of BP-lowering effect in the 24-48 h period after dose than irbesartan 300
Giuseppina Novo +4 more
doaj +1 more source
Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
Role of aliskiren in blood pressure control and renoprotection
, 2011 Hernán TrimarchiDepartment of Medicine, Division of Nephrology, Hospital Británico de Buenos Aires, Buenos Aires, ArgentinaAbstract: Patients with chronic renal disease are at increased risk for the development of cardiovascular ...
Hernan Trimarchi +1 more
core +1 more source
International Journal of Endocrinology, 2019 Background and Objectives. Thyroid hormones have an important role in the growth and development of various tissues including the kidney, which is the major site of renin release and the consequent angiotensin and aldosterone formation.
Susan A. S. Farhadi, Kawa F. Dizaye
doaj +1 more source
Frontiers in Physiology, 2019 We previously demonstrated that ureteral obstruction is associated with a urinary concentrating defect and reduced expression of renal aquaporins (AQPs), in which the renin–angiotensin system (RAS) may play an important role.
Shan Hu +10 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2020 Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, which is accompanied by progressive joint damage and disability. The intolerability of conventional antirheumatic drugs by some patients necessitates the search for effective antirheumatic ...
Amany A. Azouz +2 more
doaj +1 more source
Kidney & Blood Pressure Research, 2023 Introduction: Renin-angiotensin system inhibitors have been reported to exert protective effects against organ damage and failure; however, the impact of the direct renin inhibitor as monotherapy has not been assessed.
Yasufumi Seki +8 more
doaj +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2924-2936, August 2026.Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen +8 more
wiley +1 more source
Aging Cell, Volume 25, Issue 8, August 2026.Apiotrichum‐centered gut fungal network disturbance correlates with increased arterial stiffness. Five driver genera including Apiotrichum, Mycothermus, Flavocillium, Hyaloscypha, and Microscypha regulate the interaction shift. Thirty‐nine metabolites comprising organic acids, fatty acyls, and sucrose target vasoconstriction regulators CYP11B2, ROCK2 ...
Jiarui Chen +9 more
wiley +1 more source
Formal Total Synthesis of Aliskiren
, 2015 The efficient and selective formal total synthesis of aliskiren is described. Aliskiren, a renin inhibitor drug, has received considerable attention, primarily because it is the first of the renin inhibitor drugs to be approved by the FDA.
Peters, Byron K., +7 more
core +1 more source