Results 131 to 140 of about 191,241 (287)

The Alkylation of Acetoacetic Ester by Toluenesulphonic Esters. [PDF]

, 1935
C. NARAYANAN NAIR, D. H. PEACOCK
openalex   +1 more source

Germanium‐Based Long‐Conjugation Xanthene Fluorophores for Bioimaging in Optimal NIR‐II Sub‐Window

Aggregate, EarlyView.
An NIR‐II dye (EGe5) integrates germanium‐enhanced vibrational suppression and extended conjugation, achieving unprecedented brightness in the optimal NIR‐IIx sub‐window. This design enables high‐contrast visualization of intestinal vasculature and renal labeling, overcoming traditional signal limitations. The tailored spectral properties highlight its
Jin Li, Qiming Xia, Jiayi Li, Xiaoming Yu, Zhe Feng, Yuhuang Zhang, Tianxiang Wu, Zhongmin Xu, Hui Lin, Jun Qian   +9 more
wiley   +1 more source

Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA‐Charge Neutral Linkages for Enhanced Splice‐Switching Antisense Oligonucleotides

Angewandte Chemie, EarlyView.
Splice‐switching oligonucleotides are used to treat severe genetic conditions including Duchenne Muscular Dystrophy, but new chemistries are urgently required to improve their efficacy. In this work locked nucleic acid (LNA) is coupled to different charge neutral DNA backbones which are studied by structural, thermodynamic, and biological methods.
Alice Kennett, Lillian Lie, Martin Flerin, Belma Zengin Kurt, Ysobel R. Baker, Alyssa C. Hill, Abinaya Ramesh, Matthew J.A. Wood, Debashis Dhara, Afaf H. El‐Sagheer, Fernanda Duarte, Tom Brown   +11 more
wiley   +2 more sources

AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing

Advanced Intelligent Discovery, EarlyView.
AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley   +1 more source

Superbasic Anionic Calcium Alkyl Complexes: Templated Twofold Deprotonation of Benzene

Angewandte Chemie, EarlyView.
A family of molecular anionic calcium alkyl complexes is described. Compared with their neutral analogues, these anionic systems show markedly higher basicity, exemplified by the templated twofold deprotonation of benzene to give an inverse‐crown areneide complex.
Li Feng Lim, Ryan Huo, Flynn C. Attard, Morteza Jamshidi, Alireza Ariafard, Fabian Kallmeier, Jamie Hicks   +6 more
wiley   +2 more sources

WE USE HARSHAW CATALYTIC GRADE CHEMICALS for alkylation · isomerization · polymerization [PDF]

, 1946

openalex   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

Advanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang, Lin Li, Long Cheng, Yujie Liu, Zhaoqing Liu, Jiangpeng Wu, Pengyi Zhang, Jiarui Wang, Dekui Zhang, Shuyan Li   +9 more
wiley   +1 more source

Synthesis and Application of Bioactive N‐Functionalized Aziridines

Angewandte Chemie, EarlyView.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan, Samya Samanta, Nan Qiu, Alexander Adibekian, David C. Powers   +4 more
wiley   +2 more sources

Rapid Assembly of the Salvileucalin B Norcaradiene Core [PDF]

, 2010
Preparation of the polycyclic core of the cytotoxic natural product salvileucalin B is described. The key feature of this synthetic strategy is a copper-catalyzed intramolecular arene cyclopropanation to provide the central norcaradiene.
Levin, Sergiy, Nani, Roger R., Reisman, Sarah E.   +2 more
core   +1 more source

Synthesis of N‐Substituted 4‐Pyridones From Skipped Diynones via Intramolecular Base or Ag(I)‐Catalyzed Hydroamination

Asian Journal of Organic Chemistry, EarlyView.
A general protocol for the synthesis of N‐substituted 4‐pyridones from skipped diynones is presented via a base or Ag(I)‐catalyzed hydroamination pathway. Abstract Cs2CO3 or CF3COOAg catalyze the intramolecular 6‐endo hydroamination of the Z‐enaminones derived from the Michael‐type addition of primary amines to skipped diynones, yielding N‐substituted ...
Elisavet‐Maria Zantioti‐Chatzouda, Stavroula‐Aikaterini Kaplani, Eleni‐Maria Stroda, Nikolaos Eleftheriadis, Manolis Stratakis   +4 more
wiley   +1 more source