Thiol-linked alkylation of RNA to assess expression dynamics
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady state but obscures the intracellular dynamics of RNA transcription, processing and decay.
Veronika A. Herzog+9 more
semanticscholar +1 more source
Direct C2–H alkylation of indoles driven by the photochemical activity of halogen-bonded complexes
A light-driven metal-free protocol for the synthesis of sulfone-containing indoles under mild conditions is reported. Specifically, the process is driven by the photochemical activity of halogen-bonded complexes formed upon complexation of a sacrificial ...
Martina Mamone+4 more
doaj +1 more source
Synthesis and structures of O-anthrylmethyl-substituted hexahomotrioxacalix[3]arenes [PDF]
O-Alkylation of 7,15,23-tri-tert-butyl-25,26,27-trihydroxy-2,3,10,11,18,19-hexahomo-3,11,19-trioxacalix[3]arene (1H₃) with 9-chloromethylanthracene 5 was carried out under different reaction conditions.
Ikejiri, Yusuke+5 more
core +1 more source
Lead-Halide Perovskites for Photocatalytic α-Alkylation of Aldehydes.
Cost-effective and efficient photocatalysis are highly desirable in chemical synthesis. Here we demonstrate that readily prepared suspensions of APbBr3 (A = Cs or methylammonium (MA)) type perovskite colloids (ca.
Xiaolin Zhu+4 more
semanticscholar +1 more source
Synthesis and evaluation of a novel ionophore based on a thiacalix[4]arene derivative bearing imidazole units [PDF]
O-Alkylation of the flexible thiacalix[4]arene 1 with 2-chloromethyl-1-methyl-1H-imidazole 2 in the presence of Na₂CO₃ or K₂CO₃ afforded mono-O-alkylation product 3 in 29–51% yield, along with recovery of the starting compound.
Elsegood, Mark R. J.+8 more
core +3 more sources
Alkylation of Magnesium Enamide with Alkyl Chlorides and Fluorides. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Eiichi Nakamura+3 more
openaire +5 more sources
Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis.
DNA-encoded library (DEL) technology is a powerful tool commonly used by the pharmaceutical industry for the identification of compounds with affinity to biomolecular targets. Success in this endeavor lies in sampling diverse chemical libraries. However,
J. Phelan+7 more
semanticscholar +1 more source
Photoelectrochemical C-H Alkylation of Heteroarenes with Organotrifluoroborates.
A photoelectrochemical method for the C-H alkylation of heteroarenes with organotrifluoroborates has been developed. The merger of electrocatalysis and photoredox catalysis provides a chemical oxidant-free approach for the generation and ...
Hong Yan, Z. Hou, Hai‐Chao Xu
semanticscholar +1 more source
Stability and activity of Zn/MCM-41 materials in toluene alkylation: Microwave irradiation vs continuous flow [PDF]
Zn/MCM-41 mesoporous materials have been prepared via classic wet impregnation, employing zinc nitrate as precursor and tested for activity and stability in the Friedel-Crafts alkylation of toluene with benzyl chloride under microwave irradiation and ...
Alves, Diego+6 more
core +3 more sources
Experimental validation of computational fluid dynamic codes (CFD) for liquid-solid risers in clean alkylation processes [PDF]
This manuscript, based on the presentation given by one of the authors (M.P. Dudukovic) at the Technological and Engineering Forum in Pančevo, May 21 2002, summarizes the use of the computer automated radioactive particle tracking (CARPT) and gamma ...
Duduković Milorad P.+3 more
doaj +1 more source