Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones [PDF]
, 2009 A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively.
Bernardini, Martina +3 more
core +1 more source
On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan. [PDF]
, 2016 A Friedel-Crafts alkylation is described that efficiently transforms tryptophan-containing peptides into macrocycles of varying ring connectivity. Factors are surveyed that influence the distribution of regioisomers, with a focus on indole C3-alkylations
Curtin, Brice H +5 more
core +1 more source
Study on the Alkylation Reactions of N(7)-Unsubstituted 1,3-Diazaoxindoles
Molecules, 2017 The chemistry of the 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (1,3-diazaoxindole) compound family, possessing a drug-like scaffold, is unexplored. In this study, the alkylation reactions of N(7)-unsubstituted 5-isopropyl-1,3-diazaoxindoles bearing ...
Eszter Kókai +5 more
doaj +1 more source
Molecules, 2021 Marine polysaccharides are part of the huge seaweeds resources and present many applications for several industries. In order to widen their potential as additives or bioactive compounds, some structural modifications have been studied.
Tiphaine Wong +6 more
doaj +1 more source
Catalytic Alkylation of Brown Coal and Peat
Eurasian Chemico-Technological Journal, 2012 The alcohol alkylation of low-grade metamorphic coal and peat in the presence of mineral and organic acids was studied using FTIR, NMR, and GC-MS. The impact of the reaction conditions on the yield of extractable matter was investigated experimentally ...
S. I. Zherebtsov, Z. R. Ismagilov
doaj +1 more source
Synthesis, screening, and sequencing of cysteine-rich one-bead one-compound peptide libraries. [PDF]
, 2008 Cysteine-rich peptides are valued as tags for biarsenical fluorophores and as environmentally important reagents for binding toxic heavy metals. Due to the inherent difficulties created by cysteine, the power of one-bead one-compound (OBOC) libraries has
Greaves, John +3 more
core +2 more sources
Room-Temperature, Base-Mediated Selective Synthesis of 2-(Arylamino)ethanols and 2-Aryloxyethanols
SynOpen, 2019 A simple and efficient protocol for base-mediated selective synthesis of 2-(arylamino)ethanols from primary aromatic amines and 2-aryloxyethanols from phenols, promoted by K2CO3 has been achieved under mild conditions.
Rahul B. Sonawane +3 more
doaj +1 more source
Direct C2–H alkylation of indoles driven by the photochemical activity of halogen-bonded complexes
Beilstein Journal of Organic Chemistry, 2023 A light-driven metal-free protocol for the synthesis of sulfone-containing indoles under mild conditions is reported. Specifically, the process is driven by the photochemical activity of halogen-bonded complexes formed upon complexation of a sacrificial ...
Martina Mamone +4 more
doaj +1 more source
Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones [PDF]
, 2013 2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl ...
Beasley, Benjamin +3 more
core +1 more source
Alkylation of 2,4-(1H,3H)-Quinazolinediones with Dialkyl Carbonates Under Microwave Irradiations
Molecules, 2009 Alkylation is a very important chemical reaction which modifies the biological properties of drugs. Quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties.We now report application of a practical ...
Martha Cecilia Meza +4 more
doaj +1 more source