Results 21 to 30 of about 253,250 (328)
Thiol-linked alkylation of RNA to assess expression dynamics
Nature Methods, 2017 Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady state but obscures the intracellular dynamics of RNA transcription, processing and decay.
Veronika A. Herzog +9 more
semanticscholar +1 more source
Poly(thioether) vitrimers via transalkylation of trialkylsulfonium salts [PDF]
, 2017 Vitrimers are permanently cross-linked organic polymers that can be reshaped, molded, and recycled without loss of network integrity. Herein, we report poly(thioether) networks, prepared through a straightforward thiol-ene photopolymerization, that can ...
Hendriks, Benjamin +3 more
core +1 more source
Lead-Halide Perovskites for Photocatalytic α-Alkylation of Aldehydes.
Journal of the American Chemical Society, 2019 Cost-effective and efficient photocatalysis are highly desirable in chemical synthesis. Here we demonstrate that readily prepared suspensions of APbBr3 (A = Cs or methylammonium (MA)) type perovskite colloids (ca.
Xiaolin Zhu +4 more
semanticscholar +1 more source
3-(2-Diisopropylaminoethyl)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione
Molbank, 2022 Thiazolidine-2,4-dione core is widely used in the medicinal chemistry of different types of potential drug-like small molecules. In the present work, the synthesis of a novel non-condensed thiazolidine-2,4-dione-bearing derivative is reported by the two ...
Serhii Holota +3 more
doaj +1 more source
On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan. [PDF]
, 2016 A Friedel-Crafts alkylation is described that efficiently transforms tryptophan-containing peptides into macrocycles of varying ring connectivity. Factors are surveyed that influence the distribution of regioisomers, with a focus on indole C3-alkylations
Curtin, Brice H +5 more
core +1 more source
Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis.
Journal of the American Chemical Society, 2019 DNA-encoded library (DEL) technology is a powerful tool commonly used by the pharmaceutical industry for the identification of compounds with affinity to biomolecular targets. Success in this endeavor lies in sampling diverse chemical libraries. However,
J. Phelan +7 more
semanticscholar +1 more source
Regioselective Alkylation of an Oxonaphthalene-Annelated Pyrrol System
Molbank, 2009 The regioselective alkylation of an oxonaphthalene-annelated pyrrole system is reported. The regioselectivity of alkylation can be controlled by the selection of the solvent.
Helmut Spreitzer, Christiane Puschmann
doaj +1 more source
Meitan kexue jishu, 2023 Coal-tar pitch (CTP) is a substance produced by ambient and/or vacuum distillation of high-temperature coal tar, although CTP has a large yield in China, however its wide application is limited due to its high toxicity.
ZHANG Wenshuo +5 more
doaj +1 more source
Visible Light-Enabled Direct Decarboxylative N-Alkylation.
Angewandte Chemie, 2020 Development of efficient and selective C-N bond-forming reactions from abundant feedstock chemicals remains a central theme in organic chemistry, due to the key roles of amines in synthesis, drug discovery and materials science.
V. Nguyen +6 more
semanticscholar +1 more source
Unanticipated differences between α- and γ-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates [PDF]
, 2006 Hairpin polyamide–chlorambucil conjugates containing an {alpha}-diaminobutyric acid ({alpha}-DABA) turn moiety are compared to their constitutional isomers containing the well-characterized {gamma}-DABA turn.
Chou, C. James +4 more
core +4 more sources