Alkylating Agents Stronger than Alkyl Triflates [PDF]
Journal of the American Chemical Society, 2004 A new class of potent electrophilic "R(+)" alkylating agents has been developed using weakly nucleophilic carborane anions as leaving groups. These reagents, R(CHB(11)Me(5)X(6)) (R = Me, Et, and i-Pr; X = Cl, Br), are prepared via metathesis reactions with conventional alkylating agents such as alkyl triflates, using the high oxophilicity of silylium ...
Kato, Tsuyoshi +4 more
openaire +3 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2015 The asymmetric unit of the title compound, C48H54O5S4·N(C2H5)4+·Cl−, contains two tetra-tert-butyl-[(benzoyl)methoxy]-trihydroxy-tetrathiacalix[4]arene molecules, two tetraethylammonium cations and two chloride anions. The two calixarene molecules in the
Mehmet Akkurt +4 more
doaj +1 more source
Alkylation of N-substituted 2-phenylacetamides: Benzylation of N-(4-nitrophenyl)-2-phenylacetamide [PDF]
Journal of the Serbian Chemical Society, 2002 N-(4-Nitrophenyl)-2-phenylacetamide was alkylated with benzyl chloride in the presence of powdered potassium hydroxide at different temperatures and in various solvents in order to establish the reactivity and orientation in the reaction.
Janković Vida D. +2 more
doaj +1 more source
Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones [PDF]
, 2009 A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively.
Bernardini, Martina +3 more
core +1 more source
Engineered Enzymes Enable Selective N‐Alkylation of Pyrazoles With Simple Haloalkanes
Angewandte Chemie, 2020 Selective alkylation of pyrazoles could solve a challenge in chemistry and streamline synthesis of important molecules. Here we report catalyst‐controlled pyrazole alkylation by a cyclic two‐enzyme cascade.
Ludwig L. Bengel +5 more
semanticscholar +1 more source
DNA crosslinking and biological activity of a hairpin polyamide–chlorambucil conjugate [PDF]
, 2003 A prototype of a novel class of DNA alkylating agents, which combines the DNA crosslinking moiety chlorambucil (Chl) with a sequence-selective hairpin pyrrole-imidazole polyamide ImPy-beta-ImPy-gamma-ImPy-beta-Dp (polyamide 1), was evaluated for its ...
Beerman, Terry A. +5 more
core +2 more sources
Oxidation and alkylation stresses activate ribosome-quality control
Nature Communications, 2019 Oxidation and alkylation of nucleobases are known to disrupt their base-pairing properties within RNA. It is, however, unclear whether organisms have evolved general mechanism(s) to deal with this damage.
Liewei L. Yan +4 more
semanticscholar +1 more source
Aramid Nanomaterials of Various Morphologies: Preparation and Mechanical Property Enhancement
Frontiers in Chemistry, 2020 Aramid nanofibers (ANFs) are a novel type of promising nanoscale building blocks for high-performance nanocomposites. Conventionally, ANFs are used to composite with polymers containing polar groups such as –OH and –NH2 since those polymers can interact ...
Congcong Dong +7 more
doaj +1 more source
Alkylation of N-substituted-2-phenylacetamides [PDF]
Journal of the Serbian Chemical Society, 2004 Various N-substituted phenylacetamides were alkylated using different alkylating agents under neutral and basic conditions. Reactions were performed at different reaction temperatures and in various solvents. Also, a number of various catalysts were used
Mijin Dušan Ž. +2 more
doaj +1 more source
Chemical, Electronic, and Electrical Properties of Alkylated Ge(111) Surfaces [PDF]
, 2010 The use of Ge in semiconductor electronics has been constrained by the lack of a simple method of passivating the crystal surface. Toward that end, we have explored the utility of chemically bonded hydrocarbon monolayers.
Brunschwig, Bruce S. +2 more
core +2 more sources