Chemistry Proceedings, 2021 Azide derivatives of isatins were the initial materials needed for click chemistry, so as to form 1,2,3-triazoles in order to synthesize the hybrid compounds of 1,2,3-triazole–isatin with monosaccharide moieties.
Nguyen Minh Tri +11 more
doaj +1 more source
Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
Advanced Healthcare Materials, EarlyView.A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Novel sulfur and selenium containing bis-α-amino acids from 4-hydroxyproline [PDF]
, 2010 The synthesis of new substituted prolines carrying at C-4 a second α-amino acid residue is reported. The amino acid, l-cysteine or l-selenocysteine, is linked to the proline ring through the sulfur or the selenium atom, respectively.
CAPUTO, ROMUALDO +4 more
core +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
Synthesis and regioselective N- and O-alkylation of 1H- or 3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones (8-azaxanthines) and transformation of their 3-alkyl derivatives into 1-alkyl isomers [PDF]
, 2008 Several alkylating agents, for example alkyl halides and dimethyl sulfate, were employed in aprotic Solvents Under a variety of conditions for the alkylation of mono- and disubstituted 1H- or 3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones, which ...
Islam, Rafiqul, Nagamatsu, Tomohisa
core +1 more source
Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Harnessing Carbenoid Reactivity From Imidazoles and Oxiranes
Advanced Synthesis &Catalysis, EarlyView.The combination of azole compounds and oxiranes exhibits carbenoid reactivity at elevated temperatures, as demonstrated by the successful benzoin condensation of aromatic aldehydes. Using this catalytic system to polymerize bifunctional aldehyde/oxirane monomers yields thermosets with glass transition temperatures above 100°C.
Matthias R. Steiner +4 more
wiley +1 more source
Shape Selective Alkylation of Biphenyl with 1-octene on ((Al+C3H7Cl)+C2H4) Catalysts [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2003 Alkylation of biphenyl with 1-octene was investigated using ((Al+C3H7Cl)+C2H4) catalysts. The catalytic activity of ((Al+C3H7Cl)+C2H4) for the alkylation was studied at different temperatures, mol ratios of biphenyl to 1-octene, reaction times and ...
Sevil Veli (Veliyeva)
doaj
Synthesis of Secondary Amines via Self-Limiting Alkylation of N-Aminopyridinium Salts [PDF]
, 2023 Pritam Roychowdhury +4 more
openalex +1 more source
Ti–Pd Alloys as Heterogeneous Catalysts for Hydrogen Autotransfer Reaction and Catalytic Improvement by Hydrogenation Effects [PDF]
, 2019 Ti−Pd alloys were investigated as heterogeneous catalysts for hydrogen autotransfer reactions. This is the first reported study of alloys as catalysts for hydrogen‐borrowing reactions using alcohols.
Kondo Ryota +8 more
core +1 more source