Results 91 to 100 of about 17,659 (225)

A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres [PDF]

, 2010
The catalytic enantioselective synthesis of densely functionalized organic molecules that contain all-carbon quaternary stereocentres is a challenge to modern chemical methodology.
A Chieffi, AG Doyle, AG Doyle, Brian M. Stoltz, David E. White, DC Behenna, DE White, F Wu, G Bencivenni, G Helmchen, G Poli, H Li, J Christoffers, J-G Shim, JA Keith, Jan Streuff, JP Das, JT Mohr, JT Mohr, JT Mohr, JT Mohr, LE Overman, MM Abelman, MS Taylor, N Mase, NH Sherden, NT Patil, SC Marinescu, Scott C. Virgil, W Shu, X Liao, Y Hamashima   +31 more
core   +3 more sources

Formal Synthesis of the Akuammiline Alkaloid (±)‐Strictamine via a (4 + 2) Annulation Reaction With a Donor–Acceptor Cyclobutane

Helvetica Chimica Acta, Volume 109, Issue 4, April 2026.
We report a concise formal synthesis of (±)‐strictamine via a silylium‐catalyzed (4 + 2) annulation of a donor–acceptor cyclobutane, achieved in 13 steps from tryptamine. ABSTRACT The akuammiline alkaloids are complex monoterpene indole natural products with a rigid cage‐like architecture and diverse biological activities.
Clément Tanguy, Emma G. L. Robert, Jerome Waser   +2 more
wiley   +1 more source

Reductively Stable Platinum Catalyst Enabling Metallaphotoredox Reductive Allylation of Ketones, Aldehydes, and Imines

ChemistryEurope
This work demonstrates the catalytic reductive allylation of ketones, aldehydes, and imines using a synergistic platinum/photoredox catalyst system. Notably, this method is applicable even to acetophenone derivatives, affording homoallylic alcohols that ...
Junpei Shimosato, Kousei Nishimura, Bunta Fukuyo, Yohei Shimizu, Masaya Sawamura, Yusuke Masuda   +5 more
doaj   +1 more source

Indium-Mediated Allylation of Carbonyl Compounds in Ionic Liquids: Effect of Salts in Ionic Liquids

Molecules, 2018
The In-mediated allylation of carbonyl compounds can be performed in various types of solvents including ionic liquids. However, we have found that in [bmim][BF4] (where bmim = 1-butyl-3-methylimidazolium), the In-mediated coupling of crotyl bromide with
Tsunehisa Hirashita, Fusako Takahashi, Takayuki Noda, Yuji Takagi, Shuki Araki   +4 more
doaj   +1 more source

Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts. [PDF]

, 2019
Although much effort has been spent on the enantioselective synthesis of tertiary alkyl fluorides, the synthesis of compounds containing such a stereogenic center within an array of stereocenters, particularly two vicinal ones, remains a synthetic ...
Hartwig, John F, He, Zhi-Tao, Jiang, Xingyu   +2 more
core  

Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media

Molecules, 2012
An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described.
Roberta A. Oliveira, Paulo H. Menezes, Caio F. Melo, Juliano C. R. Freitas, Fernanda C. G. Barbosa   +4 more
doaj   +1 more source

Stereoselective synthesis of the naturally occurring 2-pyranone dodoneine [PDF]

, 2008
The first total synthesis of the naturally occurring dihydropyranone dodoneine is reported. Asymmetric allylations were used for the stereoselective generation of the two stereogenic centers.
Boschi, Boucard, Denmark, Duthaler, Evans, Fürstner, Grubbs, Grubbs), Hall, Iimura, Jafarpour, Jones, Marco, Ouedraogo, Ramachandran, Ramachandran, Schwarz, Smith III, Trnka, Umarye   +19 more
core   +2 more sources

Rapid assembly of highly-functionalised difluorinated cyclooctenones via ring-closing metathesis [PDF]

, 2002
Building block methodology from trifluoroethanol and ringclosing metathesis using a Fürstner modification of Grubbs’ conditions allows the rapid synthesis of novel difluorinated ...
Kariuki, Benson M., Owton, W. Martin, Percy, Jonathan, Pintat, Stephane, Smith, Clive A., Spencer, Neil S, Thomas, Andrew C, Watson, Martin   +7 more
core   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources

Boron: A key element in radical reactions [PDF]

, 2017
Boron derivatives are becoming key reagents in radical chemistry. Here, we describe reactions where an organoboron derivative is used as a radical initiator, a chain-transfer reagent, and a radical precursor.
Beauseigneur, Alice, Becattini, Barbara, Brecht-Forster, Andrea, Darmency, Vincent, Kandhasamy, Sarkunam, Montermini, Florian, Ollivier, Cyril, Panchaud, Philippe, Pozzi, Davide, Renaud, Philippe, Scanlan, Eoin Martin, Schaffner, Arnaud-Pierre, Weber, Valéry   +12 more
core