Results 81 to 90 of about 17,659 (225)

Back to the Electrofuture: Named Reactions Powered by Electroorganic Syntheses

ChemSusChem, Volume 19, Issue 7, 14 April 2026.
Bridging classical named reactions with modern electroorganic chemistry, this review presents how electrochemical strategies can revive and reinterpret historically significant transformations, highlighting their emerging potential as sustainable alternatives in contemporary organic synthesis.
Debajit Maiti, Yoonji Heo, Geon Kang, Min Kim, Isaac Choi   +4 more
wiley   +1 more source

Rh(II)/Pd(0) Dual Catalysis: Carbenoid N-H Insertion/Allylation Cascade Reaction to Construct Highly Functionalized and Polysubstituted Pyrrolidines

Molecules
In the category of drugs approved by the U.S. FDA, pyrrolidine is the most frequently used core of five-membered nonaromatic heterocycles containing nitrogen.
Maocheng Tang, Xianyan Jiao, Deping He, Ji-Xing Zhao, Ping Liu, Chun-Tian Li   +5 more
doaj   +1 more source

5-(tert-Butyldimethylsilyloxy)-1-(2-chloro-5,8-dimethoxyquinolin-3-yl)-3-methylenepentan-1-ol

Molbank, 2012
Novel 5-(tert-butyldimethylsilyloxy)-1-(2-chloro-5,8-dimethoxyquinolin-3-yl)-3-methylenepentan-1-ol (7) was prepared via allylation of 2-chloro-5,8-dimethoxyquinoline-3-carbaldehyde (6) with functionalized allylic iodide as tert-butyl-(3-(iodomethyl)but ...
Linda Bouarata, Dahmane Tebbani, Paul Mosset   +2 more
doaj   +1 more source

The Reaction Mechanism of the Enantioselective Tsuji Allylation: Inner-Sphere and Outer-Sphere Pathways, Internal Rearrangements, and Asymmetric C–C Bond Formation [PDF]

, 2012
We use first principles quantum mechanics (density functional theory) to report a detailed reaction mechanism of the asymmetric Tsuji allylation involving prochiral nucleophiles and nonprochiral allyl fragments, which is consistent with experimental ...
Behenna, Douglas C., Goddard, William A., III, Keith, John A., Ma, Sandy, Marinescu, Smaranda C., Mohr, Justin T., Nielsen, Robert J., Oxgaard, Jonas, Sherden, Nathaniel H., Stoltz, Brian M.   +9 more
core   +2 more sources

Expanded Substrate Pattern of the Ene‐Reductase‐Catalyzed Reduction of Activated C═N Bonds to Yield Prim‐Amines

ChemCatChem, Volume 18, Issue 8, 28 April 2026.
Ene reductases known for the reduction of C═C double bonds were shown to reduce C═N bonds, thus (a) selected oximes bearing two ester groups attached to the oximo moiety were reduced to the aliphatic amine moiety, as well as (b) a nitro group and a (c) hydrazone moiety was accepted as well.
Willem B. Breukelaar, Frieda A. Sorgenfrei, Manuela Panić, Svila Stelzer, Silvia M. Glueck, Wolfgang Kroutil   +5 more
wiley   +1 more source

Chelation-Assisted Substrate-Controlled Asymmetric Lithiation-Allylboration of Chiral Carbamate 1,2,4-Butanetriol Acetonide

Molecules, 2015
The lithiation of 2-(2,2-dimethyl-1,3-dioxolan-4-yl)ethyl diisopropylcarbamate (1) is achieved freely by sec-butyllithium in diethylether with high lk-diastereoselectivity: the bicyclic chelate complexes 3a and 3b are reacted with electrophiles to form ...
Adeem Mahmood, Hamad Z. Alkhathlan, Saima Parvez, Merajuddin Khan, Sohail A. Shahzad   +4 more
doaj   +1 more source

A general enantioselective route to the chamigrene natural product family [PDF]

, 2010
Described in this report is an enantioselective route toward the chamigrene natural product family. The key disconnections in our synthetic approach include sequential enantioselective decarboxylative allylation and ring-closing olefin metathesis to form
Grubbs, Robert H., Seashore-Ludlow, Brinton A., Stewart, Ian C., Stoltz, Brian M., White, David E.   +4 more
core   +2 more sources

Indole as a Directing Group for Nonaromatic C–H Activation in Palladium‐Catalyzed Cross‐Dehydrogenative Coupling With β‐Ketoesters

ChemistryEurope, Volume 4, Issue 4, April 2026.
A palladium‐catalyzed cross‐dehydrogenative coupling (CDC) connects the α‐carbon of β‐ketoesters with the C3‐benzylic position of indoles, forging C(sp3)‐C(sp3) bonds under mild oxidative conditions. This transformation uncovers an unprecedented directing effect of indolic π‐system, which engages in coordination with palladium to guide site‐selective C(
Anton A. Nechaev, Samat Tussupbayev, Anton Bannykh, Matias Lönnblad, Andrey Belyaev, Petri M. Pihko, Vsevolod A. Peshkov   +6 more
wiley   +1 more source

APLICAÇÃO DE AMIDOXIMAS COMO CATALISADORES DA REAÇÃO DE ALILAÇÃO POR ALILTRIFLUOROBORATO DE POTÁSSIO EM MEIO BIFÁSICO

Química Nova
We describe the application of an amidoxime as catalyst in the synthesis of homoallylic alcohols from the allylation reaction of aldehydes with different features using potassium allyltrifluoroborate. The reaction was conducted with a catalytic amount of
Dmistocles de Andrade, João Rufino de Freitas Filho, Juliano Carlo Rufino Freitas   +2 more
doaj   +1 more source

Synthesis of alkaloids by a diastereoselective allylation of chiral N-sulfinyl imines [PDF]

, 2016
The indium-promoted allylation of chiral N-sulfinyl imines represents a useful and versatile procedure to prepare chiral protected homoallyl amines in a diastereoselective manner. Desulfinylation under acidic conditions liberates easily the corresponding
Foubelo, Francisco, Yus, Miguel
core   +1 more source