Results 71 to 80 of about 17,659 (225)
Studies towards the synthesis of hyperireflexolide A
Beilstein Journal of Organic Chemistry, 2018 The first approach to hyperireflexolide A, based on the synthesis of γ-lactone-fused cyclopentane 5, a functionalized key intermediate, is presented. Compound 5 is involved in hydrolysis, α-allylation at C-8 and α-methylation at C-10 stereoselectively ...
G. Hari Mangeswara Rao
doaj +1 more source
Transient [3,3] Cope rearrangement of 3,3-dicyano-1,5-dienes: computational analysis and 2-step synthesis of arylcycloheptanes. [PDF]
, 2018 A simple and modular route to arylcycloheptene scaffolds is reported. The two-step route from Knoevenagel adducts and allylic electrophiles is made possible through the design of a Cope rearrangement that utilizes a "traceless" activating group to ...
Fereyduni, Ehsan +4 more
core +1 more source
A catalytic asymmetric total synthesis of (-)-perophoramidine [PDF]
, 2014 We report a catalytic asymmetric total synthesis of the ascidian natural product perophoramidine. The synthesis employs a molybdenum-catalyzed asymmetric allylic alkylation of an oxindole nucleophile and a monosubstituted allylic electrophile as a key ...
Krüger, Sebastian +3 more
core +3 more sources
Pd‐Catalyzed C─C Bond Borylation of Biphenylenes Leading to Tri‐Ortho‐Substituted Biaryls
Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.Palladium‐catalyzed ring‐opening C─C borylation of 1‐substituted biphenylenes yields a range of o,o,o′‐trisubstituted biaryls with two ortho‐boryl groups via selective cleavage of the least hindered C─C bond. The resulting diborylated products are readily amenable to sequential, site‐selective postfunctionalization.
Robyn V. Presland +5 more
wiley +1 more source
Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis
Molecules, 2013 The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor +3 more
doaj +1 more source
The Catalytic Asymmetric Total Synthesis of Elatol [PDF]
, 2008 Described in this report is the first total synthesis of elatol, a halogenated sesquiterpene in the chamigrene natural product family. The key disconnections in our synthetic approach include an enantioselective decarboxylative allylation to form the all-
Grubbs, Robert H. +3 more
core +2 more sources
Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts
Frontiers in Chemistry, 2019 We report here selective Tsuji-Trost type allylation of Ugi adducts using a strategy based on the enhanced nucleophilicity of amide dianions. Ugi adducts derived from aromatic aldehydes were easily allylated at their peptidyl position with allyl acetate ...
Alaa Zidan +5 more
doaj +1 more source
Rhodium-catalyzed oxidative C–H allylation of benzamides with 1,3-dienes by allyl-to-allyl 1,4-Rh(III) migration [PDF]
, 2016 The Rh(III)-catalyzed oxidative C–H allylation of N-acetylbenzamides with 1,3-dienes is described. The presence of allylic hydrogens cis- to the less substituted alkene of the 1,3-diene is important for the success of these reactions. With the assistance
Burns, David J. +2 more
core +2 more sources
Molecules, 2011 Bis(oxazolinyl)phenylrhodium(III) aqua complexes, (Phebox)RhX2(H2O) [X = Cl, Br], were found to be efficient Lewis acid catalysts for the enantioselective addition of allyl- and methallyltributyltin reagents to amino aldehydes.
Hisao Nishiyama +5 more
doaj +1 more source
Boron carboxylate catalysis of homoallylboration. [PDF]
, 2014 Boron tris(trifluoroacetate) is identified as the first effective catalyst for the homoallyl- and homocrotylboration of aldehydes by cyclopropylcarbinylboronates.
Dugas, Gabrielle J +3 more
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