Results 21 to 30 of about 9,164 (193)

The Role of Alpha Defensins in Patients with Ankylosing Spondylitis [PDF]

Aktuelle Rheumatologie, 2020
Abstract Objectives Defensins are a family of antimicrobial peptides. Elevated levels of human neutrophil peptides (HNP 1–3) are seen in blood samples of patients with inflammatory bowel disease (IBD) and in many rheumatic diseases. It has been suggested that they may play a significant role in the progression and pathogenesis of these diseases ...
Pelin Oktayoglu, Nuriye Mete, Mehmet Caglayan   +2 more
openaire   +1 more source

Human Neutrophils Kill Bacillus anthracis. [PDF]

PLoS Pathogens, 2005
Bacillus anthracis spores cause natural infections and are used as biological weapons. Inhalation infection with B. anthracis, the etiological agent of anthrax, is almost always lethal, yet cutaneous infections usually remain localized and resolve ...
Anne Mayer-Scholl, Robert Hurwitz, Volker Brinkmann, Monika Schmid, Peter Jungblut, Yvette Weinrauch, Arturo Zychlinsky   +6 more
doaj   +2 more sources

Antimicrobial Peptides: Identification of two Beta-Defensins in a Teleost Fish, the European Sea Bass (Dicentrarchus labrax)

Pharmaceuticals, 2021
Beta-defensins consist in a group of cysteine-rich antimicrobial peptides (AMPs), widely found throughout vertebrate species, including teleost fish, with antimicrobial and immunomodulatory activities.
Carolina Barroso, Pedro Carvalho, José F. M. Gonçalves, Pedro N. S. Rodrigues, João V. Neves   +4 more
doaj   +1 more source

Follicular fluid expression of alpha-defensins and their role in ovulation [PDF]

Journal of Assisted Reproduction and Genetics, 2008
Defensins are cytotoxic peptides and have a well-defined role in host defense. Human alpha defensins 1-3 (HNP1-3) are primarily produced by peripheral neutrophils and constitute about 50% of the azurphil granule protein. Studies have suggested that peripheral neutrophils and the resident neutrophils in the ovary enhance the release of IL-8 and TNF ...
S, Das, M D, Bates, G S, Vince, I, Lewis-Jones, R, Gazvani   +4 more
openaire   +2 more sources

Defensin-driven viral evolution.

PLoS Pathogens, 2020
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralization of
Karina Diaz, Ciara T Hu, Youngmee Sul, Beth A Bromme, Nicolle D Myers, Ksenia V Skorohodova, Anshu P Gounder, Jason G Smith   +7 more
doaj   +1 more source

Increased expression and levels of human β defensins (hBD2 and hBD4) in adults with dental caries

Journal of Health Sciences, 2013
Introduction: Defensins are small anti-microbial peptides produced by epithelial cells. These peptides have a broad range of actions against microorganisms, including Gram-positive and Gram-negative bacteria.Human defensins are classifi ed into two ...
Girolamo Jose Barrera, Gabriela Sanchez Tortolero, Adriana Rivas, Carmen Flores, Jose Emanuele Gonzales   +4 more
doaj   +3 more sources

HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes

Antibiotics, 2020
Acute or strenuous exercise is sometimes related to upper respiratory tract infections in athletes. Practicing intense and regular exercise can lead to incorrect activation of the immune system, causing athletes to be excluded from training programs and ...
Raffaela Pero, Mariarita Brancaccio, Cristina Mennitti, Luca Gentile, Adelaide Franco, Sonia Laneri, Margherita G. De Biasi, Chiara Pagliuca, Roberta Colicchio, Paola Salvatore, Giovanni D’Alicandro, Daniela Terracciano, Michele Cennamo, Evelina La Civita, Antonietta Liotti, Cristina Mazzaccara, Giulia Frisso, Barbara Lombardo, Olga Scudiero   +18 more
doaj   +1 more source

Alleviation of Hepatic Steatosis by Alpha-Defensin Is Associated with Enhanced Lipolysis

Medicina, 2023
Background and Objectives: The neutrophilic peptide, alpha-defensin, is considered an evolving risk factor intimately linked with lipid mobilization. It was previously linked to augmented liver fibrosis. Here, we assess a potential association between alpha-defensin and fatty liver. Materials and Methods: A cohort of transgenic C57BL/6JDef+/+ male mice
Emad Maraga, Rifaat Safadi, Johnny Amer, Abd Al-roof Higazi, Rami Abu Fanne   +4 more
openaire   +3 more sources

Inhibition of defensin A and cecropin A responses to dengue virus 1 infection in Aedes aegypti

Biomédica: revista del Instituto Nacional de Salud, 2021
Introduction: It is essential to determine the interactions between viruses and mosquitoes to diminish dengue viral transmission. These interactions constitute a very complex system of highly regulated pathways known as the innate immune system of the ...
Yda Méndez, César Pacheco, Flor Herrera   +2 more
doaj   +1 more source

Expression and regulation of avian beta-defensin 8 protein in immune tissues and cell lines of chickens [PDF]

Asian-Australasian Journal of Animal Sciences, 2018
Objective Defensins are a large family of antimicrobial peptides and components of the innate immune system that invoke an immediate immune response against harmful pathogens. Defensins are classified into alpha-, beta-, and theta-defensins.
Deivendran Rengaraj, Anh Duc Truong, Hyun S. Lillehoj, Jae Yong Han, Yeong Ho Hong   +4 more
doaj   +1 more source