Results 111 to 120 of about 3,275,969 (247)

Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials

open access: yesInternational Journal of Endocrinology, 2012
Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. Research design and methods.
Gerritje S. Mijnhout   +4 more
doaj   +1 more source

Plasma protein oxidation in aging rats after alpha-lipoic acid administration

open access: yes, 2005
In the present study, we investigated whether alpha-lipoic acid administration could have prooxidant or antioxidant effect on oxidative protein damage parameters such as protein carbonyl, nitrotyrosine, advanced oxidation protein products, and protein ...
Cakatay, Ufuk, KAYALI, Refik
core   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker   +7 more
wiley   +1 more source

Effect of alpha-lipoic acid supplementation on oxidative protein damage in the streptozotocin-diabetic rat

open access: yes, 2000
An increase in oxidative stress may contribute to the development of oxidative protein damage in streptozotocin diabetic rats. In the present study, the influence of alpha-lipoic acid supplementation on plasma protein carbonyl, plasma thiol, and plasma ...
SIVAS, Ahmet   +4 more
core   +1 more source

Is Capsaicin Effective in Relieving the Symptoms of Burning Mouth Syndrome? A Systematic Review

open access: yesJournal of Oral Rehabilitation, Volume 53, Issue 10, Page 1985-1996, October 2026.
The capsaicin, administered topically or systemically, reduces pain symptoms in patients with Burning Mouth Syndrome (BMS). However, despite consistent clinical improvement, the current evidence is limited and of low certainty, highlighting the need for well‐designed studies to confirm its effectiveness. ABSTRACT Background Burning Mouth Syndrome (BMS)
Ana Paula de Andrade Silva   +7 more
wiley   +1 more source

Alpha-lipoic acid induced insulin autoimmune antibody syndrome

open access: yesThe Egyptian Journal of Internal Medicine
Background Insulin autoimmune antibody syndrome is an uncommon cause of hypoglycemia in non-diabetic individuals. We report a case of alpha-lipoic acid-induced insulin autoimmune antibody syndrome.
Karthik Baburaj, Jabir MP, Vimal MV
doaj   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida   +4 more
wiley   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

open access: yes
Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750   +19 more
core  

Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye

open access: yes, 2016
Daniel Sarezky, Aaishah R Raquib, Joshua L Dunaief, Benjamin J Kim Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Purpose: Alpha lipoic acid (ALA) is an antioxidant and ...
Sarezky D, Raquib AR, Kim BJ, Dunaief JL
core  

Efficacy of Using Alpha-Lipoic Acid in Diabetic Neuropathy

open access: yes, 2015
The article presents a review of literature and research demonstrating the effectiveness of using alpha-lipoic acid in diabetic ...
V.I. Pankiv
core   +1 more source

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