Results 111 to 120 of about 3,499,347 (226)

The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury

, 2021
OBJECTIVE: The purpose of this study is to determine the antioxidant and anti-inflammatory effects of alpha lipoic acid (ALA) on methotrexate (MTX) induced kidney injury in ...
Aykac, A., Durgut, H., Sabuncuoglu, M. Z., Aslaner, A., Gul, M., Basturk, A., Sehirli, A. O., Cakir, T., Polat, C., Bahar, L.   +9 more
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The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

Basic and Clinical Neuroscience, 2012
Introduction : Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Narges Karimi, Mitra Kamran, Mehrdad Roghani, Tourandokht Baluchnejadmojarad   +3 more
doaj   +2 more sources

Protection from spinal cord ischemia-reperfusion damage with alpha-lipoic acid preconditioning in an animal model

, 2018
Background: This study aims to investigate whether preconditioning with alpha-lipoic acid has any protective effect in neuronal damage in an experimental spinal cord ischemia-reperfusion injury ...
Kaymaz, Memduh, Gonul, Ipek Isik, Emmez, Hakan, Demirci, Harun, Yildirim, Zuhal, KUMBASAR, ULAŞ, Emmez, Gokcen   +6 more
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Evaluating the protective effect of resveratrol, Q10, and alpha-lipoic acid on radiation-induced mice spermatogenesis injury: A histopathological study

International Journal of Reproductive BioMedicine, 2019
Background Testis is one of the most sensitive organs against the toxic effect of ionizing radiation. Exposure to even a low dose of radiation during radiotherapy, diagnostic radiology, or a radiological event could pose a threat to spermatogenesis.
Masoud Najafi, Mohsen Cheki, Peyman Amini, Abdolreza Javadi, Dheyauldeen Shabeeb, Ahmed Eleojo Musa   +5 more
doaj   +1 more source

Effect of alpha-lipoic acid supplementation on oxidative protein damage in the streptozotocin-diabetic rat

, 2000
An increase in oxidative stress may contribute to the development of oxidative protein damage in streptozotocin diabetic rats. In the present study, the influence of alpha-lipoic acid supplementation on plasma protein carbonyl, plasma thiol, and plasma ...
SIVAS, Ahmet, CAKATAY, Ufuk, KAYALI, Refik, AKCAY, T, Telci, AYŞE GÜL SÜNDÜS, Cakatay, U, Telci, A, Kayali, R, Sivas, A   +8 more
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Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials

International Journal of Endocrinology, 2012
Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. Research design and methods.
Gerritje S. Mijnhout, Boudewijn J. Kollen, Alaa Alkhalaf, Nanno Kleefstra, Henk J. G. Bilo   +4 more
doaj   +1 more source

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.

Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells.
3750, Kenzo, Uehira, Akiko, Kawabe, Masahito, Suiko, 3748, Kentaro, Nishimoto, Harishkumar, Madhyastha, 3749, Yoichi, Sakakibara, Kazuo, Nishiyama, Taiji, Suda, Masao, Yamasaki, Takeaki, Okamoto, 3751, 3742, 3743, 3744, 3745, 3746, 3747   +19 more
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Investigation on the role of alpha lipoic acid in glipizide treatment in diabetic rats

International Journal of Research in Pharmaceutical Sciences, 2011
Glipizide is a second generation sulfonylurea employed for the management of diabetes. Prolonged use of glipizide as monotherapy can cause insulin resistance.
David Banji, Swetha Merugu, Otilia J.F Banji, Vijaya laxmi Chiluka, Sonia Bindu Pandra, Narsi Reddy Koppula, Vinod K.R   +6 more
doaj  

Alpha-lipoic acid induced insulin autoimmune antibody syndrome

The Egyptian Journal of Internal Medicine
Background Insulin autoimmune antibody syndrome is an uncommon cause of hypoglycemia in non-diabetic individuals. We report a case of alpha-lipoic acid-induced insulin autoimmune antibody syndrome.
Karthik Baburaj, Jabir MP, Vimal MV
doaj   +1 more source

Ameliorative Effect of Alpha Lipoic Acid on Endometriosis: An Experimental Model in Rats

, 2020
Aim:This study aims to evaluate the effects of alpha lipoic acid (ALA), which is a strong antioxidant, on endometriosis (EMS).Methods:Thirty sexually-mature, female Wistar albino rats weighing 180-220 grams were separated into three groups: sham (n=10 ...
Taylan Onat, Murat Çakır, Çakır, Murat, Onat, Taylan   +3 more
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