Results 121 to 130 of about 27,057 (295)

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4521-4549, June 2026.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Pharmacokinetics of alpha‐lipoic acid in dogs

The FASEB Journal, 2008
The objective of this study was to evaluate effect of dose and method of delivery on pharmacokinetics of orally administered dl‐alpha‐lipoic acid (ALA) in 27 healthy dogs. Three different doses of ALA (2.5, 12.5 or 25 mg/kg bodyweight) and three variations of oral administration were evaluated (capsule form after 12 hours of fasting, capsule form given
Kathy Lynn Gross, Steven C. Zicker
openaire   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Evolution of Thiosemicarbazones: From First‐ to Second‐Generation Metal Chelators and Their Reactive Oxygen Species‐Mediated Effects in Melanoma

ChemistryOpen, Volume 15, Issue 6, June 2026.
Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim, Scott D. Andrew, Christopher J. Parkinson   +2 more
wiley   +1 more source

Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals

Aging Cell, Volume 25, Issue 6, June 2026.
Supplement users have lower epigenetic biological age than non‐users. Several supplements or supplement classes are associated with some benefit on epigenetic age in either cross‐sectional or longitudinal analyses. ABSTRACT In this cross‐sectional cohort we analyzed data from 4260 “health enthusiasts” who purchased at least one saliva‐based DNA ...
Kamil Pabis, Weilan Wang, Kumar Selvarajoo, Yelena V. Budovskaya, Vincenzo Sorrentino, Jan Gruber, Brian K. Kennedy   +6 more
wiley   +1 more source

Use of Alpha Lipoic Acid in Patients with Diabetic Polyneuropathy [PDF]

, 2019
П Р Камчатнов, F.K. Dzugayeva, А В Чугунов, A.Yu. Kazakov   +3 more
openalex   +1 more source

ALPHA-LIPOIC ACID – EFFECTS AND APPLICATIONS

, 2023
Alpha-lipoic acid is one of the most powerful antioxidants used in both humans and animals. Many of its effects were proven: antioxidant, antidiabetic, anti-inflammatory, immunomodulatory, analgesic, as a growth promoter. Numerous clinical studies showed the effectiveness of alpha-lipoic acid in diseases in which the antioxidant balance was disturbed ...
openaire   +2 more sources

Clinical Diabetic Peripheral Neuropathy: Can It Be Reversed? Arguments for and Against From a NEUROdiab Debate

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Diabetic peripheral neuropathy (DPN) is a prevalent and disabling complication of diabetes, yet whether established clinical DPN is reversible remains debated. At the 35th Annual Meeting of NEUROdiab, a formal debate examined arguments ‘for’ and ‘against’ the proposition that clinical DPN can be reversed.
Gordon Sloan, Shazli Azmi, Stephanie Eid, Maryam Ferdousi, Johan Røikjer, Zoltan Kender, Luca D'Onofrio, Eleni Karlafti, Brian Callaghan, Bruce A. Perkins   +9 more
wiley   +1 more source

An Oral Antioxidant Formulation Delaying and Potentially Reversing [PDF]

, 2015
This is the final published version. It first appeared at http://clinmedlibrary.com/articles/ijdcr/ijdcr-2-023.php?jid=ijdcr.Background: The majority of dogs with diabetes mellitus develop blinding mature cataracts through the action of the enzyme aldose
Colitz, Carmen, Fitchie, Angus, Williams, David   +2 more
core   +1 more source