Results 101 to 110 of about 47,878 (245)

The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression

open access: yesJournal of Virology
Alpha-ketoglutarate-dependent dioxygenase, also known as fat mass and obesity-associated protein (FTO), is an RNA demethylase that mediates the demethylation of N6,2-O-dimethyladenosine (m6Am) and N6-methyladenosine (m6A). Both m6Am and m6A are prevalent
Ruth Verhamme   +7 more
doaj   +1 more source

First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) [PDF]

open access: yes, 2014
BACKGROUND Herpesvirus and poxvirus can infect a wide range of species: herpesvirus genetic material has been detected and amplified in five species of the superfamily Pinnipedia; poxvirus genetic material, in eight species of Pinnipedia.
Corpa, Juan Manuel   +7 more
core   +2 more sources

RNA Modifications in Health and Disease

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Changes in these components profoundly affect the m6A methylation process, leading to a range of physiological and pathological alterations. In recent years, research on the post‐translational modifications of these components has advanced, encompassing ubiquitination, phosphorylation, SUMOylation, O‐GlcNAcylation, and lactylation.
Shiqi Li   +5 more
wiley   +1 more source

Erratum to: 2017 Colorado alphaherpesvirus latency society symposium [PDF]

open access: yesJournal of NeuroVirology, 2017
On page 650, the institutional affiliation of Dr. Werner J.D. Ouwendijk was incorrectly listed as Freie Universitaet Berlin. It should instead be Erasmus MC, Rotterdam, The Netherlands.
Nicholas L, Baird, Randall J, Cohrs
openaire   +2 more sources

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao   +7 more
wiley   +1 more source

Genomic nucleotide-based distance analysis for delimiting old world monkey derived herpes simplex virus species

open access: yesBMC Genomics, 2020
Background Herpes simplex viruses form a genus within the alphaherpesvirus subfamily, with three identified viral species isolated from Old World monkeys (OWM); Macacine alphaherpesvirus 1 (McHV-1; herpes B), Cercopithecine alphaherpesvirus 2 (SA8), and ...
Aaron W. Kolb, Curtis R. Brandt
doaj   +1 more source

Directional Spread of Alphaherpesviruses in the Nervous System

open access: yesViruses, 2013
Alphaherpesviruses are pathogens that invade the nervous systems of their mammalian hosts. Directional spread of infection in the nervous system is a key component of the viral lifecycle and is critical for the onset of alphaherpesvirus-related diseases.
Lynn W. Enquist, Tal Kramer
doaj   +1 more source

Epstein-Barr virus-encoded RNAs (EBERs) complement the loss of the herpesvirus telomerase RNA (vTR) in virus-induced tumor formation [PDF]

open access: yes, 2017
Marek’s disease virus (MDV) is an alphaherpesvirus that causes fatal lymphomas in chickens and is used as a natural virus-host model for herpesvirus-induced tumorigenesis.
Kaufer, Benedikt, Kheimar, Ahmed
core   +2 more sources

Understanding causes of morbidity and mortality in Southern Hemisphere small Odontoceti: a scoping review

open access: yesMammal Review, Volume 55, Issue 2, April 2025.
This review identifies key causes of morbidity and mortality in Southern Hemisphere small Odontoceti, highlighting significant anthropogenic threats and the enhanced need for conservation strategies. Key findings include high rates of entanglements and a diverse range of infectious pathogens. Abstract Marine mammals serve as sentinels for environmental
Rebecca Souter   +3 more
wiley   +1 more source

Electric Cell-Substrate Impedance Sensing To Monitor Viral Growth and Study Cellular Responses to Infection with Alphaherpesviruses in Real Time

open access: yesmSphere, 2017
Electric cell-substrate impedance sensing (ECIS) measures changes in an electrical circuit formed in a culture dish. As cells grow over a gold electrode, they block the flow of electricity and this is read as an increase in electrical impedance in the ...
Matthew R. Pennington   +1 more
doaj   +1 more source

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