Results 141 to 150 of about 44,477 (170)

Innate Recognition of Alphaherpesvirus DNA

2015
Alphaherpesviruses include human and animal pathogens, such as herpes simplex virus type 1, which establish life-long latent infections with episodes of recurrence. The immunocompetence of the infected host is an important determinant for the outcome of infections with alphaherpesviruses. Recognition of pathogen-associated molecular patterns by pattern
Luecke, Stefanie, Paludan, Søren R
openaire   +3 more sources

Recombination in the alphaherpesvirus bovine herpesvirus 1

Veterinary Microbiology, 2006
Herpesviruses are DNA viruses characterized by a low rate of nucleotide substitution. Therefore, other mechanisms must be involved to their evolution, like recombination that can be seen as an essential evolutionary driving force of these viruses. Recombination contributes to the long-term evolution of alphaherpesviruses.
Thiry, Etienne, Muylkens, Benoît, Meurens, F., Gogev, S., Thiry, Julien, Vanderplasschen, Alain, Schynts, F.   +6 more
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Photodisinfection of Alphaherpesvirus 1 in Bovine Semen

Journal of Photochemistry and Photobiology B: Biology
Reproductive biotechnologies are widely consolidated as a methodology in cattle breeding and have an important impact on the genetic improvement of cattle herds. Semen is an important source of dissemination of pathogenic microorganisms during reproductive procedures. To ensure the sanitary quality of the semen, it is essential to consider the presence
Taise Maria, Dos Anjos Oliveira, Amanda Vargas, Teles, Maria Lúcia, Gambarini, Keyla, de Oliveira Ribeiro, Eli Silveira Alves, Ducas, Klayto José Gonçalves, Dos Santos, Carlos Jorge Pereira, Monteiro, Elisangela, de Paula Silveira Lacerda, Leonardo Pereira, Franchi, Pablo José, Gonçalves, Guilherme Rocha Lino, de Souza   +10 more
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Emerging functions of alphaherpesvirus genes

Seminars in Virology, 1993
Abstract We know from complete sequencing of three alphaherpesvirus genomes that these large DNA viruses around 70 genes. In many cases little is known of gene function. Features of predicted amino acid sequences have given a number of clues to functions, mostly for enzymes and membrane-associated proteins. Genetic analyzes have very strikingly shown
D.J. McGeoch, B.C. Barnett, C.A. MacLean
openaire   +1 more source

Alphaherpesvirus DNA replication

2007
DNA replication in alphaherpesviruses has been the subject of study in bursts over the years. Interest in the subject depends not just on simple curiosity about this central feature of the viral growth cycle, but also because DNA replication is a potentially useful target for antiviral therapy, as has already been shown with agents such as acyclovir ...
John Hay, William T. Ruyechan
openaire   +1 more source

The biology and development of vaccines for bovine alphaherpesvirus 1

Veterinary Journal
Bovine alphaherpesvirus type 1 (BoAHV-1) infections lead to compromised herd health and significantly reduced productivity of affected cattle. While BoAHV-1 may cause rhinotracheitis, conjunctivitis, genital infections, and abortions, respiratory tract infections constitute the predominant clinical disease.
S Van Drunen Littel-Van Den Hurk
exaly   +3 more sources

Antiviral Drugs Against Alphaherpesvirus

2018
The discovery of acyclovir and penciclovir has led to the development of a successful systemic therapy for treating herpes simplex virus infection and varicella-zoster virus infection, and the orally available prodrugs, valacyclovir and famciclovir, have improved antiviral treatment compliance.
openaire   +2 more sources

Alphaherpesvirus use and misuse of cellular actin and cholesterol

Veterinary Microbiology, 2010
Two major structural elements of a cell are the cytoskeleton and the lipid membranes. Actin and cholesterol are key components of the cytoskeleton and membranes, respectively, and are involved in a plethora of different cellular processes. This review summarizes and discusses the interaction of alphaherpesviruses with actin and cholesterol during ...
Herman W, Favoreel, Céline, Van den Broeke, Ann, Desplanques, Matthias, Deruelle, Geert, Van Minnebruggen, Hans, Nauwynck, Sarah, Glorieux, Nina, Van Opdenbosch, Nick, De Regge   +8 more
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