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VirusesBovine alphaherpesvirus 1 (BoAHV1) is prevalent in cattle throughout the world, whereas bovine alphaherpesvirus 5 (BoAHV5) prevalence seems restricted to some countries in South America, Australia, and other regions, mainly in the Southern Hemisphere ...
Fernando Spilki +2 more
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Innate Recognition of Alphaherpesvirus DNA
2015Alphaherpesviruses include human and animal pathogens, such as herpes simplex virus type 1, which establish life-long latent infections with episodes of recurrence. The immunocompetence of the infected host is an important determinant for the outcome of infections with alphaherpesviruses. Recognition of pathogen-associated molecular patterns by pattern
Luecke, Stefanie, Paludan, Søren R
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Viruses, 2019 The transmission of Macacine alphaherpesvirus 1 (McHV-1) from macaques, the natural host, to humans causes encephalitis. In contrast, human infection with Cercopithecine alphaherpesvirus 2 (CeHV-2), a closely related alphaherpesvirus from African vervet ...
Stefan Pohlmann +2 more
exaly +2 more sources
Alphaherpesvirus DNA replication
2007DNA replication in alphaherpesviruses has been the subject of study in bursts over the years. Interest in the subject depends not just on simple curiosity about this central feature of the viral growth cycle, but also because DNA replication is a potentially useful target for antiviral therapy, as has already been shown with agents such as acyclovir ...
John Hay, William T. Ruyechan
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Photodisinfection of Alphaherpesvirus 1 in Bovine Semen
Journal of Photochemistry and Photobiology B: BiologyReproductive biotechnologies are widely consolidated as a methodology in cattle breeding and have an important impact on the genetic improvement of cattle herds. Semen is an important source of dissemination of pathogenic microorganisms during reproductive procedures. To ensure the sanitary quality of the semen, it is essential to consider the presence
Taise Maria, Dos Anjos Oliveira +10 more
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Emerging functions of alphaherpesvirus genes
Seminars in Virology, 1993Abstract We know from complete sequencing of three alphaherpesvirus genomes that these large DNA viruses around 70 genes. In many cases little is known of gene function. Features of predicted amino acid sequences have given a number of clues to functions, mostly for enzymes and membrane-associated proteins. Genetic analyzes have very strikingly shown
D.J. McGeoch, B.C. Barnett, C.A. MacLean
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Antiviral Drugs Against Alphaherpesvirus
2018The discovery of acyclovir and penciclovir has led to the development of a successful systemic therapy for treating herpes simplex virus infection and varicella-zoster virus infection, and the orally available prodrugs, valacyclovir and famciclovir, have improved antiviral treatment compliance.
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The neurobiology of alphaherpesvirus infections.
Acta veterinaria Hungarica, 1995In this review we have tried to outline some of the recent experimental data which has contributed to our understanding the neurobiology of herpesviruses. We have attempted to draw together the threads of several different but related disciplines, i.e.
N L, Meyers, A A, Nash
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Alphaherpesvirus use and misuse of cellular actin and cholesterol
Veterinary Microbiology, 2010Two major structural elements of a cell are the cytoskeleton and the lipid membranes. Actin and cholesterol are key components of the cytoskeleton and membranes, respectively, and are involved in a plethora of different cellular processes. This review summarizes and discusses the interaction of alphaherpesviruses with actin and cholesterol during ...
Herman W, Favoreel +8 more
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