Results 61 to 70 of about 12,278 (197)

Alphavirus Virulence Determinants [PDF]

, 2021
Alphaviruses are important pathogens that continue to cause outbreaks of disease in humans and animals worldwide. Diseases caused by alphavirus infections include acute symptoms of fever, rash, and nausea as well as chronic arthritis and severe-to-fatal ...
Kenneth A. Stapleford, Margarita V. Rangel   +1 more
core   +1 more source

Granulocyte colony-stimulating factor protects against acute systemic alphavirus disease in a type I IFN-dependent manner

Frontiers in Immunology
IntroductionArthritogenic alphaviruses, including chikungunya (CHIKV) and Mayaro virus (MAYV), cause disease characterized by fever, rash, and incapacitating joint pain.
Muddassar Hameed, Muddassar Hameed, Muddassar Hameed, Pallavi Rai, Pallavi Rai, Md Shakhawat Hossain, Md Shakhawat Hossain, Andrea Daamen, Peter E. Lipsky, James Weger-Lucarelli, James Weger-Lucarelli   +10 more
doaj   +1 more source

Sea Lice (Lepeophtheirus salmonis) Harbour Putative Fish Pathogens: Insights From Illumina and Nanopore Sequencing

Journal of Fish Diseases, EarlyView.
ABSTRACT Ectoparasites that penetrate host skin can act as biological or mechanical vectors for pathogens and, in some cases, serve as reservoirs. Crustacean ectoparasites of fish are potential vectors of pathogens, which is especially relevant for obligate pathogens (e.g., Aeromonas salmonicida) with limited seawater survival. Sea lice (Lepeophtheirus
B. Klimesova, N. M. Ruane, R. Domingo‐Bretón, F. Moroni, F. Naya‐Català, J. Pérez‐Sánchez, K. O'Dwyer, O. Lyashevska, H. Rodger, A. Talbot   +9 more
wiley   +1 more source

Interferon-mediated host response in experimentally induced salmonid alphavirus 1 infection in Atlantic salmon (Salmo salar L.) [PDF]

, 2013
Salmonid alphavirus (SAV) infection in cultured salmonids causes severe economic losses across Europe. Immune protection and antiviral mechanisms of the host against SAV are poorly characterised in vivo.
Adams, Alexandra, Richards, Randolph, Thompson, Kimberly, Herath, Tharangani   +3 more
core   +1 more source

Vaccination Reduces Shedding of Salmonid Alphavirus Subtype 3, but Bacterial Co‐Infection Influences the Effect

Journal of Fish Diseases, EarlyView.
ABSTRACT Waterborne horizontal transmission of viral diseases in fish relies on the release of infectious virus particles (termed shedding) into the aquatic environment. Both the rate and duration of shedding are critical for efficient viral spread, making interventions that reduce shedding valuable for disease control.
Søren Grove, H. Craig Morton, Dhamotharan Kannimuthu, HyeongJin Roh, Ravikumar M. Chovatia, Ma Michelle Peñaranda, Dawit Ghebretnsae, Kai Ove Skaftnesmo   +7 more
wiley   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

The Role of the Opal Termination Codon in Alphavirus Pathogenesis [PDF]

, 2018
Alphaviruses are members of the Togaviridae family of viruses. These viruses are arboviruses, most often transmitted by a mosquito host. Serious outbreaks of alphavirus infection occur worldwide and affect millions of people. Currently, the greatest risk
Jones, Jennifer
core   +2 more sources

Emergence of Salmonid Alphavirus Genotype 2 in Norway—Molecular Characterization of Viral Strains Circulating in Norway and Scotland

Viruses, 2021
Pancreas disease (PD) and sleeping disease (SD), caused by an alphavirus, are endemic in European salmonid aquaculture, causing significant mortality, reduced growth and poor flesh quality. In 2010, a new variant of salmonid alphavirus emerged in Norway,
Monika J. Hjortaas, Elena Fringuelli, Adérito L. Monjane, Aase B. Mikalsen, Christine M. Jonassen, Paul Savage, Hilde Sindre   +6 more
doaj   +1 more source

Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík, Mikolaj Adamek, Tomáš Korytář   +2 more
wiley   +1 more source