Results 71 to 80 of about 10,615 (164)

Human Antibody Responses to Emerging Mayaro Virus and Cocirculating Alphavirus Infections Examined by Using Structural Proteins from Nine New and Old World Lineages

mSphere, 2018
Mayaro virus (MAYV), Venezuelan equine encephalitis virus (VEEV), and chikungunya virus (CHIKV) are vector-borne alphaviruses that cocirculate in South America.
Jessica L. Smith, Christine L. Pugh, Emily D. Cisney, Sarah L. Keasey, Carolina Guevara, Julia S. Ampuero, Guillermo Comach, Doris Gomez, Margarita Ochoa-Diaz, Robert D. Hontz, Robert G. Ulrich   +10 more
doaj   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture

Nature Communications
Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current context of global warming.
Vasiliya Kril, Michael Hons, Celine Amadori, Claire Zimberger, Laurine Couture, Yara Bouery, Julien Burlaud-Gaillard, Andrei Karpov, Denis Ptchelkine, Alexandra L. Thienel, Beate M. Kümmerer, Ambroise Desfosses, Rhian Jones, Philippe Roingeard, Laurent Meertens, Ali Amara, Juan Reguera   +16 more
doaj   +1 more source

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Alice Rhelly V. Carvalho, José Diogo E. Reis, Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Juliana da C. Lopes, Sônia das G. S. R. Pamplona, Milton N. da Silva, Cintia Lopes de Brito Magalhães, Paulo Wender P. Gomes, Consuelo Yumiko Yoshioka e Silva   +9 more
wiley   +1 more source

Molecular Screening of Black Flies (Diptera: Simuliidae) for Vector‐Borne Zoonotic Pathogens, South Moravia, Czech Republic

Zoonoses and Public Health, Volume 73, Issue 1, Page 95-106, February 2026.
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová, Kristína Mravcová, Jan Mendel, Oldřich Šebesta, Bohumil Sak, Nikola Holubová, Martin Kváč, Clifton McKee, Peter H. Adler, D. Otranto, Ivo Rudolf   +10 more
wiley   +1 more source

Host nutritional status affects alphavirus virulence, transmission, and evolution.

PLoS Pathogens, 2019
Malnourishment, specifically overweight/obesity and undernourishment, affects more than 2.5 billion people worldwide, with the number affected ever-increasing. Concurrently, emerging viral diseases, particularly those that are mosquito-borne, have spread
James Weger-Lucarelli, Lucia Carrau, Laura I Levi, Veronica Rezelj, Thomas Vallet, Hervé Blanc, Jérémy Boussier, Daniela Megrian, Sheryl Coutermarsh-Ott, Tanya LeRoith, Marco Vignuzzi   +10 more
doaj   +1 more source

An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding

mBio, 2017
Alphaviruses are members of a group of small enveloped RNA viruses that includes important human pathogens such as Chikungunya virus and the equine encephalitis viruses.
Emily A. Byrd, Margaret Kielian
doaj   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Chronic alphavirus infection of L cells.

Acta virologica, 1981
Chronic infection of L cells with Sindbis virus, induced in the absence of antiviral antibody, was studied by virological methods in combination with light and electron microscopy. Both Sindbis virus and endogenous oncovirus antigens were revealed in the cells by immunofluorescence.
T A, Ivannikova, , Karmysheva VYa, N V, Ovsyannikova, L M, Farutina   +3 more
openaire   +1 more source

RNA processing bodies are disassembled during Old World alphavirus infection

Journal of General Virology, 2019
RNA processing bodies (P-bodies) are non-membranous cytoplasmic aggregates of mRNA and proteins involved in mRNA decay and translation repression. P-bodies actively respond to environmental stresses, associated with another type of RNA granules, known as stress granules (SGs).
Lifeng Liu, Eva Weiss, Marc D. Panas, Benjamin Götte, Stina Sellberg, Bastian Thaa, Gerald M. McInerney   +6 more
openaire   +2 more sources