Results 141 to 150 of about 15,327 (237)
Characterization of the Rubella Virus Nonstructural Protease Domain and Its Cleavage Site [PDF]
, 1996 The region of the rubella virus nonstructural open reading frame that contains the papain-like cysteine protease domain and its cleavage site was expressed with a Sindbis virus vector. Cys-1151 has previously been shown to be required for the activity of
Chen, Jun-Ping +3 more
core
Journal of General Virology, 2019 The genus Alphavirus harbours mostly insect-transmitted viruses that cause severe disease in humans, livestock and wildlife. Thus far, only three alphaviruses with a host range restricted to insects have been found in mosquitoes from the Old World ...
Kyra Hermanns +8 more
semanticscholar +1 more source
Elucidation of the Epitranscriptomic RNA Modification Landscape of Chikungunya Virus
VirusesThe genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral
Belinda Baquero-Pérez +7 more
doaj +1 more source
The many ways in which alphaviruses bind to cells.
Trends in immunology, 2023 S. Raju, L. Adams, Michael S. Diamond
semanticscholar +1 more source
Interferon regulatory factor 1 protects against chikungunya virus-induced immunopathology by restricting infection in muscle cells [PDF]
, 2017 Diamond, Michael S +3 more
core +2 more sources
Alphaviral vectors for gene transfer into neurons [PDF]
, 2018 Alphaviruses are small, enveloped positive-strand RNA viruses that have been successfully transformed into expression vectors in the case of Semliki Forest virus (SFV), Sindbis virus (SIN), and Venezuelan equine encephalitis virus.
Ehrengruber, Markus
core
Functions of Alphavirus Macrodomain-containing protein nsP3 [PDF]
, 2011 Alphaviruses are positive strand RNA viruses that replicate in association with cellular membranes. The viral RNA replication complex consists of four non-structural proteins nsP1-nsP4 which are essential for viral replication.
Neuvonen, Maarit
core
VirusesAlphaviruses can replicate in arthropods and in many vertebrate species including humankind, but only in vertebrate cells do infections with these viruses result in a strong inhibition of host translation and transcription.
Iván Ventoso +3 more
doaj +1 more source
The life cycle of the alphaviruses: From an antiviral perspective.
Antiviral Research, 2022 Andrew M. Skidmore, Steven B. Bradfute
semanticscholar +1 more source