Results 41 to 50 of about 10,044 (209)
, 2016 Alphaviruses comprise a fascinating group of small, enveloped single-stranded positive-sense RNA viruses. They are usually transmitted by arthropod vectors (usually mosquitoes).
Mahalingam, Suresh +2 more
core +1 more source
Alphaviruses in Latin America and the Introduction of Chikungunya Virus [PDF]
, 2017 Alphaviruses are enveloped, single-stranded, plus-strand RNA viruses belonging to the Togaviridae family. These are zoonotics and arthropod-borne viruses (mainly mosquitoes) that are distributed nearly worldwide.
Jean-Paul Carrera +8 more
core +1 more source
Packaging signals in alphaviruses [PDF]
Journal of Virology, 1997 Alphaviruses synthesize large amounts of both genomic and subgenomic RNA in infected cells, but usually only the genomic RNA is packaged. This implies the existence of an encapsidation or packaging signal which would be responsible for selectivity. Previously, we had identified a region of the Sindbis virus genome that interacts specifically with the ...
E, Frolova, I, Frolov, S, Schlesinger
openaire +2 more sources
Direct broad-range detection of alphaviruses in mosquito extracts [PDF]
, 2007 Members of the genus Alphavirus are a diverse group of principally mosquito-borne RNA viruses. There are at least 29 species and many more subtypes of alphaviruses and some are considered potential bioweapons.
Rudnick, Karl +19 more
core +1 more source
Replication of the genome of alphaviruses [PDF]
Journal of Cell Science, 1987 ABSTRACT The genome of Semliki Forest virus (SFV) is 11 442 nucleotides with a 5′ cap-structure and a 3′ poly(A) tail of about 100 residues. The genome of the closely related Sindbis virus (SIN) is slightly longer (11 703 nucleotides). The parental RNA is first translated from the 5′ two thirds to yield; nsPl, nsP2, nsP3 and nsP4, which ...
L, Kääriäinen +3 more
openaire +2 more sources
Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Waterborne horizontal transmission of viral diseases in fish relies on the release of infectious virus particles (termed shedding) into the aquatic environment. Both the rate and duration of shedding are critical for efficient viral spread, making interventions that reduce shedding valuable for disease control.
Søren Grove +7 more
wiley +1 more source
Medical and Veterinary Entomology, EarlyView.Bauxite mining in the Amazon alters mosquito communities, favouring anthropophilic and generalist vectors while reducing species diversity and the variety of blood meal sources. Molecular analyses identified humans, tapirs and deer as the primary blood meal sources.
Mayron Mielly Morais Pacheco +8 more
wiley +1 more source
Animal Models of Alphavirus-induced Inflammatory Disease
, 2016 Animal models that reflect key aspects of human disease are invaluable tools for understanding the mechanisms of disease pathogenesis and development of treatment strategies.
Taylor, Adam +11 more
core +1 more source
Mosquitoes as Suitable Vectors for Alphaviruses [PDF]
, 2018 Alphaviruses are arthropod-borne viruses and are predominantly transmitted via mosquito vectors. This vector preference by alphaviruses raises the important question of the determinants that contribute to vector competence.
Eugene Madzokere +14 more
core +1 more source